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Increased soluble HLA in COVID-19 present a disease-related, diverse immunopeptidome associated with T cell immunity

HLA-presented antigenic peptides are central components of T cell-based immunity in infectious disease. Beside HLA molecules on cell surfaces, soluble HLA molecules (sHLA) are released in the blood suggested to impact cellular immune responses. We demonstrated that sHLA levels were significantly inc...

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Detalles Bibliográficos
Autores principales:	Nelde, Annika, Rieth, Jonas, Roerden, Malte, Dubbelaar, Marissa L., Hoenisch Gravel, Naomi, Bauer, Jens, Klein, Reinhild, Hoheisel, Tobias, Mahrhofer, Hartmut, Göpel, Siri, Bitzer, Michael, Hörber, Sebastian, Peter, Andreas, Heitmann, Jonas S., Walz, Juliane S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675079/ https://www.ncbi.nlm.nih.gov/pubmed/36439376 http://dx.doi.org/10.1016/j.isci.2022.105643

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