Cargando…

Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model

PURPOSE: Radiotherapy is one of the essential treatment modalities for nasopharyngeal carcinoma (NPC), however, radioresistance still poses challenges. Three-dimensional (3D) tumor culture models mimic the in vivo growth conditions of cells more accurately than 2D models. This study is to compare th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Yanhua, Liang, Shanshan, Gao, Jianong, Wang, Zhe, Li, Cheng, Wang, Ruoyu, Yu, Weiting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675143/ https://www.ncbi.nlm.nih.gov/pubmed/36403050 http://dx.doi.org/10.1186/s12935-022-02787-5

Ejemplares similares

IGF-1R Inhibition Suppresses Cell Proliferation and Increases Radiosensitivity in Nasopharyngeal Carcinoma Cells
por: Wang, Zhe, et al.
Publicado: (2019)

Biomarkers for enhancing the radiosensitivity of nasopharyngeal carcinoma
por: Chen, Wei, et al.
Publicado: (2015)

OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis
por: Di, Muping, et al.
Publicado: (2022)

Extracellular matrix stiffness—The central cue for skin fibrosis
por: Wang, Kang, et al.
Publicado: (2023)

Radiosensitivity-Related Genes and Clinical Characteristics of Nasopharyngeal Carcinoma
por: Dai, Yongmei, et al.
Publicado: (2020)

Organ sculpting by patterned extracellular matrix stiffness
por: Crest, Justin, et al.
Publicado: (2017)

MiR‐24 enhances radiosensitivity in nasopharyngeal carcinoma by targeting SP1
por: Kang, Min, et al.
Publicado: (2016)

RNAi-mediated knockdown of CAIX enhances the radiosensitivity of nasopharyngeal carcinoma cell line, CNE-2
por: Jiang, Liji, et al.
Publicado: (2017)

Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
por: Chen, Dong-Yuan, et al.
Publicado: (2019)

Curcumin Enhances Radiosensitization of Nasopharyngeal Carcinoma via Mediating Regulation of Tumor Stem-like Cells by a CircRNA Network
por: Zhu, Daoqi, et al.
Publicado: (2020)

Radiosensitivity enhancement by combined treatment of nimotuzumab and celecoxib on nasopharyngeal carcinoma cells
por: Huang, Jianfeng, et al.
Publicado: (2018)

Antitumor and Radiosensitization Effects of a CXCR2 Inhibitor in Nasopharyngeal Carcinoma
por: Liu, Xiaobei, et al.
Publicado: (2021)

Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
por: Jiang, Yangfu, et al.
Publicado: (2022)

Simultaneous Inhibition of EGFR and HER2 via Afatinib Augments the Radiosensitivity of Nasopharyngeal Carcinoma Cells
por: Huang, Fangling, et al.
Publicado: (2019)

Stiff Extracellular Matrix Promotes Invasive Behaviors of Trophoblast Cells
por: Cao, Jialing, et al.
Publicado: (2023)

MiR-34a Regulates Nasopharyngeal Carcinoma Radiosensitivity by Targeting SIRT1
por: Liu, Yang, et al.
Publicado: (2020)

Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells
por: Chen, Hao, et al.
Publicado: (2021)

IGF-I Induces Epithelial-to-Mesenchymal Transition via the IGF-IR–Src–MicroRNA-30a–E-Cadherin Pathway in Nasopharyngeal Carcinoma Cells
por: Wang, Ruoyu, et al.
Publicado: (2016)

Protein tyrosine phosphatase receptor type D gene promotes radiosensitivity via STAT3 dephosphorylation in nasopharyngeal carcinoma
por: Lin, Yanling, et al.
Publicado: (2021)

Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation
por: Zhu, Tong, et al.
Publicado: (2023)

The role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R
por: Liang, Zhong-Guo, et al.
Publicado: (2018)

Identification of non-invasive biomarkers for predicting the radiosensitivity of nasopharyngeal carcinoma from serum microRNAs
por: Li, Kaiguo, et al.
Publicado: (2020)

Extracellular matrix stiffness dictates Wnt expression through integrin pathway
por: Du, Jing, et al.
Publicado: (2016)

Metformin reverses the drug resistance of cisplatin in irradiated CNE-1 human nasopharyngeal carcinoma cells through PECAM-1 mediated MRPs down-regulation
por: Sun, Yingming, et al.
Publicado: (2020)

Radiosensitization Effect of Nedaplatin on Nasopharyngeal Carcinoma Cells in Different Status of Epstein-Barr Virus Infection
por: Yin, Li, et al.
Publicado: (2014)

Afatinib Reverses EMT via Inhibiting CD44-Stat3 Axis to Promote Radiosensitivity in Nasopharyngeal Carcinoma
por: Huang, Huichao, et al.
Publicado: (2022)

Stiffness of the Extracellular Matrix: A Regulator of Prostaglandins in Pulmonary Fibrosis?
por: Jandl, Katharina, et al.
Publicado: (2020)

Extracellular Matrix Stiffness: New Areas Affecting Cell Metabolism
por: Ge, Heming, et al.
Publicado: (2021)

Correction to: Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells
por: Chen, Hao, et al.
Publicado: (2021)

Correction: Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells
por: Chen, Hao, et al.
Publicado: (2023)

The Radiosensitization of Sodium Glycididazole on Nasopharyngeal Carcinoma Cells via Enhancing DNA Damage and Promoting Apoptosis
por: Min, Xiaoli, et al.
Publicado: (2019)

Analysis of differential membrane proteins related to matrix stiffness-mediated metformin resistance in hepatocellular carcinoma cells
por: Gao, Xiangyu, et al.
Publicado: (2023)

Potential protective benefits of Schisandrin B against severe acute hepatitis in children during the COVID-19 pandemic based on a network pharmacology analysis
por: Fang, Yanhua, et al.
Publicado: (2022)

To predict the radiosensitivity of nasopharyngeal carcinoma using intravoxel incoherent motion MRI at 3.0 T
por: Chen, Wen Bo, et al.
Publicado: (2017)

Discovering biomarkers of radioresistance in a radiosensitive cancer: a clinical paradox in nasopharyngeal carcinoma
por: Tan, Laura L. Y., et al.
Publicado: (2020)

Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5
por: Sun, Meiyu, et al.
Publicado: (2018)

The NRF2/KEAP1 Pathway Modulates Nasopharyngeal Carcinoma Cell Radiosensitivity via ROS Elimination
por: Zhou, Jieyu, et al.
Publicado: (2020)

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness
por: Heck, Jessica N., et al.
Publicado: (2012)

Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation
por: Hwang, Jun-Ha, et al.
Publicado: (2015)

Extracellular Matrix Stiffness and Composition Regulate the Myofibroblast Differentiation of Vaginal Fibroblasts
por: Ruiz-Zapata, Alejandra M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ru167retmq14tmasudjdmog74q