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Uterine macrophages as treatment targets for therapy of premature rupture of membranes by modified ADSC-EVs through a circRNA/miRNA/NF-κB pathway

BACKGROUND: Circular RNA (circRNA) is a type of stable non-coding RNA that modifies macrophage inflammation by sponging micro RNAs (miRNAs), binding to RNA-binding proteins, and undergoing translation into peptides. Activated M1 phenotype macrophages secrete matrix metalloproteinases to participate...

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Detalles Bibliográficos
Autores principales: Gao, Yuhua, Mi, Ningning, Zhang, Ying, Li, Xiangchen, Guan, Weijun, Bai, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675163/
https://www.ncbi.nlm.nih.gov/pubmed/36402996
http://dx.doi.org/10.1186/s12951-022-01696-z

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