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Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) is characterized by massive changes in neuronal excitation, from acute excitotoxicity to chronic hyper- or hypoexcitability. Nuclear calcium signaling pathways are involved in translating changes in synaptic inputs and neuronal activity into discrete transcri...

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Detalles Bibliográficos
Autores principales: Fröhlich, Albrecht, Olde Heuvel, Florian, Rehman, Rida, Krishnamurthy, Sruthi Sankari, Li, Shun, Li, Zhenghui, Bayer, David, Conquest, Alison, Hagenston, Anna M., Ludolph, Albert, Huber-Lang, Markus, Boeckers, Tobias, Knöll, Bernd, Morganti-Kossmann, Maria Cristina, Bading, Hilmar, Roselli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675197/
https://www.ncbi.nlm.nih.gov/pubmed/36403069
http://dx.doi.org/10.1186/s12974-022-02634-4