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Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers

PURPOSE: The vast majority of research studies that have described the links between DNA damage repair or homologous recombination deficiency (HRD) score, and tumor biology, have concerned either triple negative breast cancers or cancers with mutation of BRCA 1/2. We hypothesized that ER + /HER2- ea...

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Detalles Bibliográficos
Autores principales: Ballot, Elise, Galland, Loïck, Mananet, Hugo, Boidot, Romain, Arnould, Laurent, Desmoulins, Isabelle, Mayeur, Didier, Kaderbhai, Courèche, Ilie, Silvia, Hennequin, Audrey, Bergeron, Anthony, Derangère, Valentin, Ghiringhelli, François, Truntzer, Caroline, Ladoire, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675271/
https://www.ncbi.nlm.nih.gov/pubmed/36401316
http://dx.doi.org/10.1186/s13058-022-01572-6

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