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Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx

BACKGROUND: Children receiving cytotoxic therapy for cancer have increased risk of infection due to drug‐induced neutropenia and are therefore treated empirically for bacteremia when febrile or ill‐appearing. However, viral infections, which are not frequently life‐threatening, are the most common e...

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Detalles Bibliográficos
Autores principales: Offenbacher, Rachel, Gorlick, Joshua, Weiser, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675379/
https://www.ncbi.nlm.nih.gov/pubmed/36199156
http://dx.doi.org/10.1002/cnr2.1724
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author Offenbacher, Rachel
Gorlick, Joshua
Weiser, Daniel A.
author_facet Offenbacher, Rachel
Gorlick, Joshua
Weiser, Daniel A.
author_sort Offenbacher, Rachel
collection PubMed
description BACKGROUND: Children receiving cytotoxic therapy for cancer have increased risk of infection due to drug‐induced neutropenia and are therefore treated empirically for bacteremia when febrile or ill‐appearing. However, viral infections, which are not frequently life‐threatening, are the most common etiology of febrile episodes and there has been increased effort to differentiate patients who may have a higher risk for adverse outcomes. CASE: We performed a retrospective chart review of pediatric oncology patients diagnosed with COVID‐19 between December 20, 2021 and February 22, 2022 during the Omicron (B.1.1.529) surge at The Children's Hospital at Montefiore, a tertiary care center in the Bronx. CONCLUSION: We found that no patients in our cohort developed respiratory distress, bacteremia, or serious illness after COVID‐19 infection during the Omicron surge. Future studies will aid in understanding the relationship between community‐acquired infections and bacteremia, and this knowledge can then be applied to develop optimal infection prevention clinical care guidelines.
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spelling pubmed-96753792022-11-21 Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx Offenbacher, Rachel Gorlick, Joshua Weiser, Daniel A. Cancer Rep (Hoboken) Brief Reports BACKGROUND: Children receiving cytotoxic therapy for cancer have increased risk of infection due to drug‐induced neutropenia and are therefore treated empirically for bacteremia when febrile or ill‐appearing. However, viral infections, which are not frequently life‐threatening, are the most common etiology of febrile episodes and there has been increased effort to differentiate patients who may have a higher risk for adverse outcomes. CASE: We performed a retrospective chart review of pediatric oncology patients diagnosed with COVID‐19 between December 20, 2021 and February 22, 2022 during the Omicron (B.1.1.529) surge at The Children's Hospital at Montefiore, a tertiary care center in the Bronx. CONCLUSION: We found that no patients in our cohort developed respiratory distress, bacteremia, or serious illness after COVID‐19 infection during the Omicron surge. Future studies will aid in understanding the relationship between community‐acquired infections and bacteremia, and this knowledge can then be applied to develop optimal infection prevention clinical care guidelines. John Wiley and Sons Inc. 2022-10-05 /pmc/articles/PMC9675379/ /pubmed/36199156 http://dx.doi.org/10.1002/cnr2.1724 Text en © 2022 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Offenbacher, Rachel
Gorlick, Joshua
Weiser, Daniel A.
Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
title Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
title_full Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
title_fullStr Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
title_full_unstemmed Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
title_short Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
title_sort omicron variant of sars‐cov‐2, an epidemiologic assessment of pediatric oncology patients in the bronx
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675379/
https://www.ncbi.nlm.nih.gov/pubmed/36199156
http://dx.doi.org/10.1002/cnr2.1724
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