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Directly injected lentiviral vector–based T cell vaccine protects mice against acute and chronic viral infection

Lentiviral vector–based dendritic cell vaccines induce protective T cell responses against viral infection and cancer in animal models. In this study, we tested whether preventative and therapeutic vaccination could be achieved by direct injection of antigen-expressing lentiviral vector, obviating t...

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Detalles Bibliográficos
Autores principales: Tada, Takuya, Norton, Thomas D., Leibowitz, Rebecca, Landau, Nathaniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675446/
https://www.ncbi.nlm.nih.gov/pubmed/35972807
http://dx.doi.org/10.1172/jci.insight.161598