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IRF4 expression by lung dendritic cells drives acute but not Trm cell–dependent memory Th2 responses
Expression of the transcription factor interferon regulatory factor 4 (IRF4) is required for the development of lung conventional DCs type 2 (cDC2s) that elicit Th2 responses, yet how IRF4 functions in lung cDC2s throughout the acute and memory allergic response is not clear. Here, we used a mouse m...
Autores principales: | Camacho, Daniel F., Velez, Tania E., Hollinger, Maile K., Wang, Esther, Howard, Chanie L., Darnell, Eli P., Kennedy, Domenick E., Krishack, Paulette A., Hrusch, Cara L., Clark, Marcus R., Moon, James J., Sperling, Anne I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675458/ https://www.ncbi.nlm.nih.gov/pubmed/36194494 http://dx.doi.org/10.1172/jci.insight.140384 |
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