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Genetic inhibition of serum glucocorticoid kinase 1 prevents obesity-related atrial fibrillation

Obesity is an important risk factor for atrial fibrillation (AF), but a better mechanistic understanding of obesity-related atrial fibrillation is required. Serum glucocorticoid kinase 1 (SGK1) is a kinase positioned within multiple obesity-related pathways, and prior work has shown a pathologic rol...

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Detalles Bibliográficos
Autores principales: Bapat, Aneesh, Li, Guoping, Xiao, Ling, Yeri, Ashish, Hulsmans, Maarten, Grune, Jana, Yamazoe, Masahiro, Schloss, Maximilian J., Iwamoto, Yoshiko, Tedeschi, Justin, Yang, Xinyu, Nahrendorf, Matthias, Rosenzweig, Anthony, Ellinor, Patrick T., Das, Saumya, Milan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675459/
https://www.ncbi.nlm.nih.gov/pubmed/35998035
http://dx.doi.org/10.1172/jci.insight.160885