β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood

Puberty is associated with transient insulin resistance that normally recedes at the end of puberty; however, in overweight children, insulin resistance persists, leading to an increased risk of type 2 diabetes. The mechanisms whereby pancreatic β cells adapt to pubertal insulin resistance, and how...

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Detalles Bibliográficos
Autores principales: Castell, Anne-Laure, Goubault, Clara, Ethier, Mélanie, Fergusson, Grace, Tremblay, Caroline, Baltz, Marie, Dal Soglio, Dorothée, Ghislain, Julien, Poitout, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675460/
https://www.ncbi.nlm.nih.gov/pubmed/36107617
http://dx.doi.org/10.1172/jci.insight.160854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675460/
https://www.ncbi.nlm.nih.gov/pubmed/36107617
http://dx.doi.org/10.1172/jci.insight.160854

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