Single-cell transcriptome mapping identifies a local, innate B cell population driving chronic rejection after lung transplantation

Bronchiolitis obliterans syndrome (BOS) is the main reason for poor outcomes after lung transplantation (LTx). We and others have recently identified B cells as major contributors to BOS after LTx. The extent of B cell heterogeneity and the relative contributions of B cell subpopulations to BOS, how...

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Detalles Bibliográficos
Autores principales: Smirnova, Natalia F., Riemondy, Kent, Bueno, Marta, Collins, Susan, Suresh, Pavan, Wang, Xingan, Patel, Kapil N., Cool, Carlyne, Königshoff, Melanie, Sharma, Nirmal S., Eickelberg, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Resource and Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675462/
https://www.ncbi.nlm.nih.gov/pubmed/36134664
http://dx.doi.org/10.1172/jci.insight.156648

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