Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival

Clinical studies of cancer patients have shown that overexpression or amplification of thymidylate synthase (TS) correlates with a worse clinical outcome. We previously showed that elevated TS exhibits properties of an oncogene and promotes pancreatic neuroendocrine tumors (PanNETs) with a long late...

Descripción completa

Detalles Bibliográficos
Autores principales: Vijayakurup, Vinod, Maeng, Kyungah, Lee, Hye Seung, Meyer, Benjamin, Burkett, Sandra, Nawab, Akbar, Dougherty, Michael W., Jobin, Christian, Mahmud, Iqbal, Garrett, Timothy J., Feely, Michael, Lee, Kyoung Bun, Kaye, Frederic J., Guijarro, Maria V., Zajac-Kaye, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675466/
https://www.ncbi.nlm.nih.gov/pubmed/36048542
http://dx.doi.org/10.1172/jci.insight.147417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675466/
https://www.ncbi.nlm.nih.gov/pubmed/36048542
http://dx.doi.org/10.1172/jci.insight.147417

Ejemplares similares