Hyperglycemia exacerbates dengue virus infection by facilitating poly(A)-binding protein–mediated viral translation

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Diabetes mellitus (DM) is highly comorbid with severe dengue diseases; however, the underlying mechanisms are unclear. Patients with DM have a 1.61-fold increased risk of developing dengue hemorrhagic fever. In search of host factors involved in dengue virus (DENV) infection, we used high-glucose (H...

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Detalles Bibliográficos
Autores principales: Shen, Ting-Jing, Chen, Chia-Ling, Tsai, Tsung-Ting, Jhan, Ming-Kai, Bai, Chyi-Huey, Yen, Yu-Chun, Tsai, Ching-Wen, Tseng, Po-Chun, Yu, Chia-Yi, Lin, Chiou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675471/
https://www.ncbi.nlm.nih.gov/pubmed/36125898
http://dx.doi.org/10.1172/jci.insight.142805
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