Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis

Early-stage temporomandibular joint osteoarthritis (TMJOA) is characterized by excessive subchondral bone loss. Emerging evidence suggests that TMJ disc displacement is involved, but the pathogenic mechanism remains unclear. Here, we established a rat model of TMJOA that simulated disc displacement...

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Detalles Bibliográficos
Autores principales: Feng, Shi-Yang, Lei, Jie, Li, Yu-Xiang, Shi, Wen-Ge, Wang, Ran-Ran, Yap, Adrian Ujin, Wang, Yi-Xiang, Fu, Kai-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675482/
https://www.ncbi.nlm.nih.gov/pubmed/36173680
http://dx.doi.org/10.1172/jci.insight.158874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675482/
https://www.ncbi.nlm.nih.gov/pubmed/36173680
http://dx.doi.org/10.1172/jci.insight.158874

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