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AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas
Although Barrett’s metaplasia of the esophagus (BE) is the only known precursor lesion to esophageal adenocarcinomas (EACs), drivers of cellular transformation in BE remain incompletely understood. We use an artificial intelligence–guided network approach to study EAC initiation and progression. Key...
Autores principales: | Ghosh, Pradipta, Campos, Vinicius J., Vo, Daniella T., Guccione, Caitlin, Goheen-Holland, Vanae, Tindle, Courtney, Mazzini, Guilherme S., He, Yudou, Alexandrov, Ludmil B., Lippman, Scott M., Gurski, Richard R., Das, Soumita, Yadlapati, Rena, Curtius, Kit, Sahoo, Debashis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675486/ https://www.ncbi.nlm.nih.gov/pubmed/36134663 http://dx.doi.org/10.1172/jci.insight.161334 |
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