Cargando…

α2,6 Sialylation mediated by ST6GAL1 promotes glioblastoma growth

One of the least-investigated areas of brain pathology research is glycosylation, which is a critical regulator of cell surface protein structure and function. β-Galactoside α2,6-sialyltransferase (ST6GAL1) is the primary enzyme that α2,6 sialylates N-glycosylated proteins destined for the plasma me...

Descripción completa

Detalles Bibliográficos
Autores principales:	GC, Sajina, Tuy, Kaysaw, Rickenbacker, Lucas, Jones, Robert, Chakraborty, Asmi, Miller, C. Ryan, Beierle, Elizabeth A., Hanumanthu, Vidya Sagar, Tran, Anh N., Mobley, James A., Bellis, Susan L., Hjelmeland, Anita B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675560/ https://www.ncbi.nlm.nih.gov/pubmed/36345944 http://dx.doi.org/10.1172/jci.insight.158799

Ejemplares similares

ST6Gal1: Oncogenic signaling pathways and targets
por: GC, Sajina, et al.
Publicado: (2022)

Reactive oxygen species produced by altered tumor metabolism impacts cancer stem cell maintenance
por: Tuy, Kaysaw, et al.
Publicado: (2021)

Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation
por: Vergé, Caroline, et al.
Publicado: (2019)

Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics
por: Ankenbauer, Katherine E., et al.
Publicado: (2023)

Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics
por: Ankenbauer, Katherine E., et al.
Publicado: (2023)

Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death
por: Britain, Colleen M., et al.
Publicado: (2018)

A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1
por: Libby, Catherine J, et al.
Publicado: (2021)

ST6Gal-I–mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion
por: Rao, Tejeshwar C., et al.
Publicado: (2022)

Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells
por: Dorsett, Kaitlyn A., et al.
Publicado: (2019)

Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells
por: Britain, Colleen M., et al.
Publicado: (2020)

ST6GAL1 and α2-6 Sialylation Regulates IL-6 Expression and Secretion in Chronic Obstructive Pulmonary Disease
por: Krick, Stefanie, et al.
Publicado: (2021)

The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation
por: Zhou, Leqi, et al.
Publicado: (2019)

Phylogenetic-Derived Insights into the Evolution of Sialylation in Eukaryotes: Comprehensive Analysis of Vertebrate β-Galactoside α2,3/6-Sialyltransferases (ST3Gal and ST6Gal)
por: Teppa, Roxana E., et al.
Publicado: (2016)

Sialylation of FGFR1 by ST6Gal-I overexpression contributes to ovarian cancer cell migration and chemoresistance
por: Ou, Lingling, et al.
Publicado: (2020)

Plasma ST6GAL1 regulates IgG sialylation to control IgA nephropathy progression
por: Liu, Youxia, et al.
Publicado: (2021)

Glycomics reveal that ST6GAL1‐mediated sialylation regulates uterine lumen closure during implantation
por: Han, Kun, et al.
Publicado: (2021)

ST6GalNAc‐I promotes lung cancer metastasis by altering MUC5AC sialylation
por: Lakshmanan, Imayavaramban, et al.
Publicado: (2021)

Evidence for glycosylation as a regulator of the pigmentary system: key roles of sialyl(α2-6)gal/GalNAc-terminated glycans in melanin synthesis and transfer
por: Diwakar, Ganesh, et al.
Publicado: (2015)

Production of α2,6-sialylated IgG1 in CHO cells
por: Raymond, Céline, et al.
Publicado: (2015)

Cleavage of ST6Gal I by Radiation-Induced BACE1 Inhibits Golgi-Anchored ST6Gal I-Mediated Sialylation of Integrin β1 and Migration in Colon Cancer Cells
por: Lee, Minyoung, et al.
Publicado: (2012)

Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase
por: Holdbrooks, Andrew T., et al.
Publicado: (2020)

α2,6-Sialylation is Upregulated in Severe COVID-19 Implicating the Complement Cascade
por: Qin, Rui, et al.
Publicado: (2022)

α2,6-Sialylation Is Upregulated in Severe COVID-19, Implicating the Complement Cascade
por: Qin, Rui, et al.
Publicado: (2022)

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression
por: Bhalerao, Nikita, et al.
Publicado: (2023)

Hyper α2,6‐Sialylation Promotes CD4(+) T‐Cell Activation and Induces the Occurrence of Ulcerative Colitis
por: Fan, Qingjie, et al.
Publicado: (2023)

ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells
por: Schultz, Matthew J, et al.
Publicado: (2013)

Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer
por: Smithson, Mary, et al.
Publicado: (2022)

α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway
por: Zhao, Y, et al.
Publicado: (2017)

Convergent chemoenzymatic synthesis of O-GalNAc rare cores 5, 7, 8 and their sialylated forms
por: Gadi, Madhusudhan Reddy, et al.
Publicado: (2023)

Response of high-risk of recurrence/progression bladder tumours expressing sialyl-Tn and sialyl-6-T to BCG immunotherapy
por: Lima, L, et al.
Publicado: (2013)

Lectin-Based Assay for Glycoform-Specific Detection of α2,6-sialylated Transferrin and Carcinoembryonic Antigen in Tissue and Body Fluid
por: Ito, Hiromi, et al.
Publicado: (2018)

Sialylation of vasorin by ST3Gal1 facilitates TGF‐β1‐mediated tumor angiogenesis and progression
por: Yeo, Hui Ling, et al.
Publicado: (2019)

Deficiency in ST6GAL1, one of the two α2,6-sialyltransferases, has only a minor effect on the pathogenesis of prion disease
por: Makarava, Natallia, et al.
Publicado: (2022)

Increased Level of α2,6-Sialylated Glycans on HaCaT Cells Induced by Titanium Dioxide Nanoparticles under UV Radiation
por: Ren, Yuanyuan, et al.
Publicado: (2018)

Retraction Note: α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway
por: Zhao, Y., et al.
Publicado: (2020)

Association of State Stay-at-Home Orders and State-Level African American Population With COVID-19 Case Rates
por: Padalabalanarayanan, Sangeetha, et al.
Publicado: (2020)

ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function
por: Christie, Daniel R, et al.
Publicado: (2008)

Comprehensive landscape of the ST3GAL family reveals the significance of ST3GAL6-AS1/ST3GAL6 axis on EGFR signaling in lung adenocarcinoma cell invasion
por: Li, Jiaxuan, et al.
Publicado: (2022)

Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women
por: Engdahl, Cecilia, et al.
Publicado: (2018)

The regulatory ZFAS1/miR-150/ST6GAL1 crosstalk modulates sialylation of EGFR via PI3K/Akt pathway in T-cell acute lymphoblastic leukemia
por: Liu, Qianqian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5jn2rmrnbjptto6hqoag21op0b