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Preclinical testing of dabigatran in trypsin-dependent pancreatitis

Pancreatitis, the inflammatory disorder of the pancreas, has no specific therapy. Genetic, biochemical, and animal model studies revealed that trypsin plays a central role in the onset and progression of pancreatitis. Here, we performed biochemical and preclinical mouse experiments to offer proof of...

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Detalles Bibliográficos
Autores principales: Pesei, Zsófia Gabriella, Jancsó, Zsanett, Demcsák, Alexandra, Németh, Balázs Csaba, Vajda, Sandor, Sahin-Tóth, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675574/
https://www.ncbi.nlm.nih.gov/pubmed/36136430
http://dx.doi.org/10.1172/jci.insight.161145

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