A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis

Pleural and peritoneal metastasis accompanied by malignant pleural effusion (MPE) or malignant ascites (MA) is frequent in patients with advanced solid tumors that originate from the lung, breast, gastrointestinal tract and ovary. Regional delivery of CAR-T cells represents a new strategy to control...

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Detalles Bibliográficos
Autores principales: Ma, Qizhi, He, Xia, Zhang, Benxia, Guo, Fuchun, Ou, Xuejin, Yang, Qiyu, Shu, Pei, Chen, Yue, Li, Kai, Gao, Ge, Zhu, Yajuan, Qin, Diyuan, Tang, Jie, Li, Xiaoyu, Jing, Meng, Zhao, Jian, Mo, Zeming, Liu, Ning, Zeng, Yao, Zhou, Kexun, Feng, Mingyang, Liao, Weiting, Lei, Wanting, Li, Qiu, Li, Dan, Wang, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675732/
https://www.ncbi.nlm.nih.gov/pubmed/36402752
http://dx.doi.org/10.1038/s41392-022-01198-2

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