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PRDM15 interacts with DNA-PK-Ku complex to promote radioresistance in rectal cancer by facilitating DNA damage repair

Neoadjuvant radiotherapy is a standard treatment for locally advanced rectal cancer, however, resistance to chemoradiotherapy is one of the main obstacles to improving treatment outcomes. The goal of this study was to explore the role of PRDM15 involved in the radioresistance of colorectal cancer an...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Liu, Tingting, Yu, Guanyu, Wang, Hang, Du, Zhipeng, Chen, Yuanyuan, Yang, Nan, Cao, Kun, Liu, Chunlei, Wan, Zhijie, Shen, Hui, Gao, Fu, Yang, Yanyong, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675803/
https://www.ncbi.nlm.nih.gov/pubmed/36402747
http://dx.doi.org/10.1038/s41419-022-05402-7