Cargando…

Lipid-Polymer Hybrid Nanocarriers for Oral Delivery of Felodipine: Formulation, Characterization and Ex Vivo Evaluation

Purpose: Felodipine, is a calcium-channel antagonist used for hypertension and angina pectoris. It is practically insoluble in aqueous media and shows low oral bioavailability (15%-20%). This investigation aims to prepare and characterize oral felodipine lipid-polymer hybrid nanocarriers (LPHNs) to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Drais, Hayder Kadhim, Hussein, Ahmed Abbas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tabriz University of Medical Sciences 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675922/ https://www.ncbi.nlm.nih.gov/pubmed/36415635 http://dx.doi.org/10.34172/apb.2022.081

Ejemplares similares

Bromelain Loaded Lipid-Polymer Hybrid Nanoparticles for Oral Delivery: Formulation and Characterization
por: Ebrahimian, Mahboubeh, et al.
Publicado: (2022)

Nanovesicles for transdermal delivery of felodipine: Development, characterization, and pharmacokinetics
por: Yusuf, Mohd, et al.
Publicado: (2014)

Nanocarriers for Biomedicine: From Lipid Formulations to Inorganic and Hybrid Nanoparticles
por: Kashapov, Ruslan, et al.
Publicado: (2021)

Polymer–Lipid Pharmaceutical Nanocarriers: Innovations by New Formulations and Production Technologies
por: Bochicchio, Sabrina, et al.
Publicado: (2021)

Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies
por: Bhaskar, Kesavan, et al.
Publicado: (2009)

A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment
por: Gupta, Madhu, et al.
Publicado: (2022)

Use of Lipid Nanocarriers to Improve Oral Delivery of Vitamins
por: Hsu, Ching-Yun, et al.
Publicado: (2019)

Implications of biomimetic nanocarriers in targeted drug delivery
por: Al-Hetty, Hussein Riyadh Abdul Kareem, et al.
Publicado: (2023)

Hydrocortisone-Loaded Lipid–Polymer Hybrid Nanoparticles for Controlled Topical Delivery: Formulation Design Optimization and In Vitro and In Vivo Appraisal
por: Alsaidan, Omar Awad, et al.
Publicado: (2023)

Current approaches in lipid-based nanocarriers for oral drug delivery
por: Plaza-Oliver, María, et al.
Publicado: (2021)

Inhalable Formulation Based on Lipid–Polymer Hybrid Nanoparticles for the Macrophage Targeted Delivery of Roflumilast
por: Craparo, Emanuela F., et al.
Publicado: (2022)

Lyophilized phytosomal nanocarriers as platforms for enhanced diosmin delivery: optimization and ex vivo permeation
por: Freag, May S, et al.
Publicado: (2013)

Formulation optimization, in vitro and in vivo evaluation of niosomal nanocarriers for enhanced topical delivery of cetirizine
por: Aldawsari, Mohammed F., et al.
Publicado: (2023)

Effect of felodipine on indomethacin-induced gastric ulcers in rats
por: Akbaş, Nergis, et al.
Publicado: (2023)

Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study
por: Ramadan, Alyaa, et al.
Publicado: (2011)

Preparation, characterization, and evaluation (in-vitro, ex-vivo, and in-vivo) of naturosomal nanocarriers for enhanced delivery and therapeutic efficacy of hesperetin
por: Gurav, Shailendra, et al.
Publicado: (2022)

Lipid-Based Nanocarriers for RNA Delivery
por: Xue, Hui Yi, et al.
Publicado: (2015)

Bioinspired Lipid Nanocarriers for RNA Delivery
por: Golubovic, Alex, et al.
Publicado: (2023)

Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation
por: Shafique, Muhammad, et al.
Publicado: (2023)

Simvastatin Solid Lipid Nanoparticles for Oral Delivery: Formulation Development and In vivo Evaluation
por: Padhye, S. G., et al.
Publicado: (2013)

A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization
por: Kola Srinivas, Navya Sree, et al.
Publicado: (2016)

Formulation and In-Vitro/Ex-Vivo Characterization of Pregelled Hybrid Alginate–Chitosan Microparticles for Ocular Delivery of Ketorolac Tromethamine
por: Fathalla, Zeinab, et al.
Publicado: (2023)

Evaluation of Brain Targeting and Antipsychotic Activity of Nasally Administrated Ziprasidone Lipid–Polymer Hybrid Nanocarriers
por: Abo El-Enin, Hadel A., et al.
Publicado: (2023)

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
por: Siddiqi, Farah H., et al.
Publicado: (2019)

Exploring molecular reorientations in amorphous and recrystallized felodipine at the microscopic level
por: Pajzderska, A., et al.
Publicado: (2020)

Nucleoside-Lipid-Based Nanocarriers for Sorafenib Delivery
por: Benizri, Sebastien, et al.
Publicado: (2018)

Oral Rehabilitation of a Patient With Generalized Inflammatory Gingival Overgrowth Exacerbated by Felodipine: A Case Report
por: Wan Jamil, Wan Ahmad Faiz, et al.
Publicado: (2022)

Optimization, ex vivo permeation, and stability study of lipid nanocarrier loaded gelatin capsules for treatment of intermittent claudication
por: Sallam, Marwa Ahmed, et al.
Publicado: (2015)

Optimization of Novel Naproxen-Loaded Chitosan/Carrageenan Nanocarrier-Based Gel for Topical Delivery: Ex Vivo, Histopathological, and In Vivo Evaluation
por: Noreen, Sobia, et al.
Publicado: (2021)

Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel
por: Qin, Lu, et al.
Publicado: (2021)

Lipid-drug conjugates: a potential nanocarrier system for oral drug delivery applications
por: Banerjee, Subham, et al.
Publicado: (2018)

Lipid-based nano-formulation platform for eplerenone oral delivery as a potential treatment of chronic central serous chorioretinopathy: in-vitro optimization and ex-vivo assessment
por: Abdelhakeem, Eman, et al.
Publicado: (2021)

Dual Drug Loaded Lipid Nanocarrier Formulations for Topical Ocular Applications
por: Youssef, Ahmed Adel Ali, et al.
Publicado: (2022)

Formulation of lipid polymer hybrid nanoparticles of the phytochemical Fisetin and its in vivo assessment against severe acute pancreatitis
por: Awadeen, Randa Hanie, et al.
Publicado: (2023)

Transdermal Delivery of α-Aminophosphonates as Semisolid Formulations—An In Vitro-Ex Vivo Study
por: Kocsis, Dorottya, et al.
Publicado: (2023)

Formulation and in Vitro, ex Vivo and in Vivo Evaluation of Elastic Liposomes for Transdermal Delivery of Ketorolac Tromethamine
por: Nava, Guadalupe, et al.
Publicado: (2011)

STAT6 siRNA Matrix-Loaded Gelatin Nanocarriers: Formulation, Characterization, and Ex Vivo Proof of Concept Using Adenocarcinoma Cells
por: Youngren, Susanne R., et al.
Publicado: (2013)

In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis
por: Tagalakis, Aristides D., et al.
Publicado: (2018)

The challenges of oral drug delivery via nanocarriers
por: Reinholz, Jonas, et al.
Publicado: (2018)

Chitosan-functionalized lipid-polymer hybrid nanoparticles for oral delivery of silymarin and enhanced lipid-lowering effect in NAFLD
por: Liang, Jun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l4b51vuur9gqgdlgjoepjtm6cj