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Phytest: quality control for phylogenetic analyses

MOTIVATION: The ability to automatically conduct quality control checks on phylogenetic analyses is becoming more important with the increase in genetic sequencing and the use of real-time pipelines e.g. in the SARS-CoV-2 era. Implementations of real-time phylogenetic analyses require automated test...

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Detalles Bibliográficos
Autores principales: Wirth, Wytamma, Mutch, Simon, Turnbull, Robert, Duchene, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676013/
https://www.ncbi.nlm.nih.gov/pubmed/36205601
http://dx.doi.org/10.1093/bioinformatics/btac664
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author Wirth, Wytamma
Mutch, Simon
Turnbull, Robert
Duchene, Sebastian
author_facet Wirth, Wytamma
Mutch, Simon
Turnbull, Robert
Duchene, Sebastian
author_sort Wirth, Wytamma
collection PubMed
description MOTIVATION: The ability to automatically conduct quality control checks on phylogenetic analyses is becoming more important with the increase in genetic sequencing and the use of real-time pipelines e.g. in the SARS-CoV-2 era. Implementations of real-time phylogenetic analyses require automated testing to make sure that problems in the data are caught automatically within analysis pipelines and in a timely manner. Here, we present Phytest (version 1.1) a tool for automating quality control checks on sequences, trees and metadata during phylogenetic analyses. RESULTS: Phytest is a phylogenetic analysis testing program that easily integrates into existing phylogenetic pipelines. We demonstrate the utility of Phytest with real-world examples. AVAILABILITY AND IMPLEMENTATION: Phytest source code is available on GitHub (https://github.com/phytest-devs/phytest) and can be installed via PyPI with the command ‘pip install phytest’. Extensive documentation can be found at https://phytest-devs.github.io/phytest/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-96760132022-11-21 Phytest: quality control for phylogenetic analyses Wirth, Wytamma Mutch, Simon Turnbull, Robert Duchene, Sebastian Bioinformatics Applications Note MOTIVATION: The ability to automatically conduct quality control checks on phylogenetic analyses is becoming more important with the increase in genetic sequencing and the use of real-time pipelines e.g. in the SARS-CoV-2 era. Implementations of real-time phylogenetic analyses require automated testing to make sure that problems in the data are caught automatically within analysis pipelines and in a timely manner. Here, we present Phytest (version 1.1) a tool for automating quality control checks on sequences, trees and metadata during phylogenetic analyses. RESULTS: Phytest is a phylogenetic analysis testing program that easily integrates into existing phylogenetic pipelines. We demonstrate the utility of Phytest with real-world examples. AVAILABILITY AND IMPLEMENTATION: Phytest source code is available on GitHub (https://github.com/phytest-devs/phytest) and can be installed via PyPI with the command ‘pip install phytest’. Extensive documentation can be found at https://phytest-devs.github.io/phytest/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2022-10-07 /pmc/articles/PMC9676013/ /pubmed/36205601 http://dx.doi.org/10.1093/bioinformatics/btac664 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Wirth, Wytamma
Mutch, Simon
Turnbull, Robert
Duchene, Sebastian
Phytest: quality control for phylogenetic analyses
title Phytest: quality control for phylogenetic analyses
title_full Phytest: quality control for phylogenetic analyses
title_fullStr Phytest: quality control for phylogenetic analyses
title_full_unstemmed Phytest: quality control for phylogenetic analyses
title_short Phytest: quality control for phylogenetic analyses
title_sort phytest: quality control for phylogenetic analyses
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676013/
https://www.ncbi.nlm.nih.gov/pubmed/36205601
http://dx.doi.org/10.1093/bioinformatics/btac664
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