Cargando…

Regulatory mechanism of Scutellaria baicalensis Georgi on bone cancer pain based on network pharmacology and experimental verification

CONTEXT: Scutellaria baicalensis Georgi (SBG) may relieve bone cancer pain (BCP) by regulating cell proliferation, angiogenesis, and apoptosis. OBJECTIVE: The mechanism of SBG in the treatment of BCP remains to be further explored. METHODS: The active compounds and targets of SBG were obtained from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Aitao, Guo, Dongmei, Cheng, Hongyu, Jiang, Hui, Liu, Xiaojuan, Tie, Muer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676018/ https://www.ncbi.nlm.nih.gov/pubmed/36415861 http://dx.doi.org/10.7717/peerj.14394

Ejemplares similares

Scutellaria baicalensis georgi is a promising candidate for the treatment of autoimmune diseases
por: Wang, Jun, et al.
Publicado: (2022)

Chemical and pharmacological evaluations on the extract of Scutellaria baicalensis Georgi (Huang-Qin) prepared by various extraction methods
por: Zhou, Xuelin, et al.
Publicado: (2016)

Flavonoids from Scutellaria baicalensis Georgi are effective to treat cerebral ischemia/reperfusion
por: Shang, Yazhen, et al.
Publicado: (2013)

Molecular characterization of carotenoid biosynthetic genes and carotenoid accumulation in Scutellaria baicalensis Georgi
por: Tuan, Pham Anh, et al.
Publicado: (2015)

Potential Therapeutic Mechanism of Scutellaria baicalensis Georgi against Ankylosing Spondylitis Based on a Comprehensive Pharmacological Model
por: Li, Xu, et al.
Publicado: (2022)

Study on the interaction mechanism between DNA and the main active components in Scutellaria baicalensis Georgi
por: Sun, Yantao, et al.
Publicado: (2008)

Scutellaria baicalensis Georgi and Their Natural Flavonoid Compounds in the Treatment of Ovarian Cancer: A Review
por: Cai, Jiaying, et al.
Publicado: (2023)

Selection and evaluation of reference genes for qRT-PCR of Scutellaria baicalensis Georgi under different experimental conditions
por: Wang, Wentao, et al.
Publicado: (2021)

The Key Target and Molecular Mechanism of the Volatile Component of Scutellaria baicalensis Georgi in Acute Lung Injury Based on Network Pharmacology
por: Zhu, Guosong, et al.
Publicado: (2021)

Anti-Bladder-Tumor Effect of Baicalein from Scutellaria baicalensis Georgi and Its Application In Vivo
por: Wu, Jin-Yi, et al.
Publicado: (2013)

Water Deficit Affected Flavonoid Accumulation by Regulating Hormone Metabolism in Scutellaria baicalensis Georgi Roots
por: Yuan, Yuan, et al.
Publicado: (2012)

Optimization of the extraction of total flavonoids from Scutellaria baicalensis Georgi using the response surface methodology
por: Liu, Yanqing, et al.
Publicado: (2014)

Deep Eutectic Solvent-Based Ultrahigh Pressure Extraction of Baicalin from Scutellaria baicalensis Georgi
por: Wang, Hui, et al.
Publicado: (2018)

Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresis
por: Yu, Ke, et al.
Publicado: (2007)

Metabolomic and Transcriptomic Profiling Uncover the Underlying Mechanism of Color Differentiation in Scutellaria baicalensis Georgi. Flowers
por: Wang, Defu, et al.
Publicado: (2022)

Electrostimulation improves plant growth and modulates the flavonoid profile in aeroponic culture of Scutellaria baicalensis Georgi
por: Grzelka, Kajetan, et al.
Publicado: (2023)

Adsorption and Purification of Baicalin from Scutellaria baicalensis Georgi Extract by Ionic Liquids (ILs) Grafted Silica
por: Fan, Yunchang, et al.
Publicado: (2021)

Two types of O‐methyltransferase are involved in biosynthesis of anticancer methoxylated 4′‐deoxyflavones in Scutellaria baicalensis Georgi
por: Cui, Meng‐Ying, et al.
Publicado: (2021)

Geochemical characteristics and growth suitability assessment of Scutellaria baicalensis Georgi in the Earth’s critical zone of North China
por: Li, Xia, et al.
Publicado: (2022)

Systematic Analysis and Functional Characterization of R2R3-MYB Genes in Scutellaria baicalensis Georgi
por: Wang, Wentao, et al.
Publicado: (2022)

Post-Harvest Processing Methods Have Critical Roles in the Contents of Active Ingredients of Scutellaria baicalensis Georgi
por: Zhang, Liuwei, et al.
Publicado: (2022)

Biology of Scutellaria baicalensis Georgi (Lamiaceae) from Different Ecological and Geographical Places of Growth during Introduction
por: Pshenichkina, Yu. A.
Publicado: (2022)

Exploring the Potential Molecular Mechanism of Scutellaria baicalensis Georgi in the Treatment of Gastric Cancer Based on Network Pharmacological Analysis and Molecular Docking Technology
por: Tu, Yi, et al.
Publicado: (2021)

Exploring the Mechanism of Scutellaria baicalensis Georgi Efficacy against Oral Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking Analysis
por: Hou, Fanfan, et al.
Publicado: (2021)

Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice
por: Jeong, Kukhuon, et al.
Publicado: (2011)

Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression
por: Liu, Jinxin, et al.
Publicado: (2015)

Characterizing the Neuroprotective Effects of S/B Remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) in Spinal Cord Injury
por: Tu, Tsung-Hsi, et al.
Publicado: (2019)

Genome-Wide Identification and Characterization of the WRKY Gene Family in Scutellaria baicalensis Georgi under Diverse Abiotic Stress
por: Zhang, Caijuan, et al.
Publicado: (2022)

Improvement of Bronchial Immune Hypersensitivity Reaction Using Extracts from Chrysanthemum morifolium Ramatuelle and Scutellaria baicalensis Georgi
por: Cho, Kyoungwon, et al.
Publicado: (2021)

Scutellaria baicalensis Georgi regulates REV-ERBα/BMAL1 to protect against skin aging in mice
por: Sun, Guanghui, et al.
Publicado: (2022)

Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review
por: Song, Jia-Wen, et al.
Publicado: (2020)

Mechanisms underlying attenuation of apoptosis of cortical neurons in the hypoxic brain by flavonoids from the stems and leaves of Scutellaria baicalensis Georgi
por: Miao, Guangxin, et al.
Publicado: (2014)

Korean Scutellaria baicalensis Georgi flavonoid extract induces mitochondrially mediated apoptosis in human gastric cancer AGS cells
por: Venkatarame Gowda Saralamma, Venu, et al.
Publicado: (2017)

Therapeutic Potential of Bioactive Components from Scutellaria baicalensis Georgi in Inflammatory Bowel Disease and Colorectal Cancer: A Review
por: Jang, Jung Yoon, et al.
Publicado: (2023)

Scutellaria baicalensis in the Treatment of Hepatocellular Carcinoma: Network Pharmacology Analysis and Experimental Validation
por: Cai, Xin, et al.
Publicado: (2023)

Proteome profiling of lipopolysaccharide induced L6 rat skeletal muscle cells response to flavonoids from Scutellaria baicalensis Georgi
por: Kim, Jin A, et al.
Publicado: (2014)

Scutellaria baicalensis Georgi extract protects against alcohol-induced acute liver injury in mice and affects the mechanism of ER stress
por: DONG, QINGQING, et al.
Publicado: (2016)

Bifunctional effects of O-methylated flavones from Scutellaria baicalensis Georgi on melanocytes: Inhibition of melanin production and intracellular melanosome transport
por: Kudo, Michiko, et al.
Publicado: (2017)

Comparative Investigation for Rotten Xylem (kuqin) and Strip Types (tiaoqin) of Scutellaria baicalensis Georgi Based on Fingerprinting and Chemical Pattern Recognition
por: Cao, Xuexiao, et al.
Publicado: (2019)

The Combination of Scutellaria baicalensis Georgi and Sophora japonica L. ameliorate Renal Function by Regulating Gut Microbiota in Spontaneously Hypertensive Rats
por: Guan, Yiqing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i404pe5vmnajniup6beugsq78h