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A duplex-specific nuclease based electrochemical biosensor for the assay of SARS-CoV-2 RdRp RNA
We present a method for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection based on the dual amplification effect of duplex-specific nuclease (DSN). In this scheme, we cleverly employed a 2-OMe-RNA modified DNA to prevent hairpin nucleic acid from being digested by DSN. The targe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676167/ https://www.ncbi.nlm.nih.gov/pubmed/36423689 http://dx.doi.org/10.1016/j.ab.2022.114983 |