Prospective bacterial and fungal sources of hyaluronic acid: A review

The unique biological and rheological properties make hyaluronic acid a sought-after material for medicine and cosmetology. Due to very high purity requirements for hyaluronic acid in medical applications, the profitability of streptococcal fermentation is reduced. Production of hyaluronic acid by r...

Descripción completa

Detalles Bibliográficos
Autores principales: Shikina, E.V., Kovalevsky, R.A., Shirkovskaya, A.I., Toukach, Ph.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676211/
https://www.ncbi.nlm.nih.gov/pubmed/36420162
http://dx.doi.org/10.1016/j.csbj.2022.11.013
_version_ 1784833541156110336
author Shikina, E.V.
Kovalevsky, R.A.
Shirkovskaya, A.I.
Toukach, Ph.V.
author_facet Shikina, E.V.
Kovalevsky, R.A.
Shirkovskaya, A.I.
Toukach, Ph.V.
author_sort Shikina, E.V.
collection PubMed
description The unique biological and rheological properties make hyaluronic acid a sought-after material for medicine and cosmetology. Due to very high purity requirements for hyaluronic acid in medical applications, the profitability of streptococcal fermentation is reduced. Production of hyaluronic acid by recombinant systems is considered a promising alternative. Variations in combinations of expressed genes and fermentation conditions alter the yield and molecular weight of produced hyaluronic acid. This review is devoted to the current state of hyaluronic acid production by recombinant bacterial and fungal organisms.
format Online
Article
Text
id pubmed-9676211
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Research Network of Computational and Structural Biotechnology
record_format MEDLINE/PubMed
spelling pubmed-96762112022-11-22 Prospective bacterial and fungal sources of hyaluronic acid: A review Shikina, E.V. Kovalevsky, R.A. Shirkovskaya, A.I. Toukach, Ph.V. Comput Struct Biotechnol J Review The unique biological and rheological properties make hyaluronic acid a sought-after material for medicine and cosmetology. Due to very high purity requirements for hyaluronic acid in medical applications, the profitability of streptococcal fermentation is reduced. Production of hyaluronic acid by recombinant systems is considered a promising alternative. Variations in combinations of expressed genes and fermentation conditions alter the yield and molecular weight of produced hyaluronic acid. This review is devoted to the current state of hyaluronic acid production by recombinant bacterial and fungal organisms. Research Network of Computational and Structural Biotechnology 2022-11-10 /pmc/articles/PMC9676211/ /pubmed/36420162 http://dx.doi.org/10.1016/j.csbj.2022.11.013 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Shikina, E.V.
Kovalevsky, R.A.
Shirkovskaya, A.I.
Toukach, Ph.V.
Prospective bacterial and fungal sources of hyaluronic acid: A review
title Prospective bacterial and fungal sources of hyaluronic acid: A review
title_full Prospective bacterial and fungal sources of hyaluronic acid: A review
title_fullStr Prospective bacterial and fungal sources of hyaluronic acid: A review
title_full_unstemmed Prospective bacterial and fungal sources of hyaluronic acid: A review
title_short Prospective bacterial and fungal sources of hyaluronic acid: A review
title_sort prospective bacterial and fungal sources of hyaluronic acid: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676211/
https://www.ncbi.nlm.nih.gov/pubmed/36420162
http://dx.doi.org/10.1016/j.csbj.2022.11.013
work_keys_str_mv AT shikinaev prospectivebacterialandfungalsourcesofhyaluronicacidareview
AT kovalevskyra prospectivebacterialandfungalsourcesofhyaluronicacidareview
AT shirkovskayaai prospectivebacterialandfungalsourcesofhyaluronicacidareview
AT toukachphv prospectivebacterialandfungalsourcesofhyaluronicacidareview

Ejemplares similares