Cargando…
Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study
OBJECTIVE: To study specific information on trends in incidence, mortality, disability-adjusted life years (DALY) and the corresponding trends among five sociodemographic index regions, 21 regions, and 204 countries for decision-making, which would enable policymakers to distribute limited resources...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676237/ https://www.ncbi.nlm.nih.gov/pubmed/36419793 http://dx.doi.org/10.3389/fmed.2022.1003605 |
_version_ | 1784833547770527744 |
---|---|
author | Cheng, Lin-Can Li, Hao-Yang Gong, Qin-Qin Huang, Cheng-Yang Zhang, Chao Yan, Jin-Zhu |
author_facet | Cheng, Lin-Can Li, Hao-Yang Gong, Qin-Qin Huang, Cheng-Yang Zhang, Chao Yan, Jin-Zhu |
author_sort | Cheng, Lin-Can |
collection | PubMed |
description | OBJECTIVE: To study specific information on trends in incidence, mortality, disability-adjusted life years (DALY) and the corresponding trends among five sociodemographic index regions, 21 regions, and 204 countries for decision-making, which would enable policymakers to distribute limited resources and devise policies more rationally. METHODS: Data on uterine fibroids (UNs) from 1990 to 2019, including incidence, mortality, and DALYs, were obtained from the 2019 Global Burden of Disease Study. An estimated annual percentage change (EAPC) was calculated to assess morbidity, mortality, and DALY trends. RESULTS: The incident cases of UFs increased from 5,769,658 (95%UI, 7,634,3995–4,274,824) incidences in 1990 to 9,643,336 (95%UI, 7,178,053-12,714,741) incidences in 2017, and the age-standardized incidence rate was steady at 225.67/100,000 persons (95%UI, 167.33–298.87) in 1990 to 241.18/100,000 persons (95%UI, 179,45–318.02) in 2019. The incidence ratio in the high sociodemographic index (SDI) region showed a unimodal distribution, with peaks in 2005. Between 2009 and 2017, the age-standardized death rate of UFs declined globally, especially in low-SDI and low-middle SDI regions. In contrast with 860,619 DALYs (95%UI, 473,067-1,505,289) in 1990, the number of DALYs was 1,378,497 (95%UI, 710,915-2,475,244) in 2019, which had increased significantly, whereas the age-standardized DALY rate decreased expressively with an EAPC of −1.93 (95%CI, from −2.16 to −1.71). CONCLUSION: The global burden of UFs increased between 1990 and 2019, and the incidences and DALYs increased prominently worldwide, while the deaths from UFs had no evident growth. Lower SDI regions carried an incremental burden of UFs, while disease reduction was observed in higher SDI regions. It is high time we paid attention to the underprivileged regional quality of life and health protection. |
format | Online Article Text |
id | pubmed-9676237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96762372022-11-22 Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study Cheng, Lin-Can Li, Hao-Yang Gong, Qin-Qin Huang, Cheng-Yang Zhang, Chao Yan, Jin-Zhu Front Med (Lausanne) Medicine OBJECTIVE: To study specific information on trends in incidence, mortality, disability-adjusted life years (DALY) and the corresponding trends among five sociodemographic index regions, 21 regions, and 204 countries for decision-making, which would enable policymakers to distribute limited resources and devise policies more rationally. METHODS: Data on uterine fibroids (UNs) from 1990 to 2019, including incidence, mortality, and DALYs, were obtained from the 2019 Global Burden of Disease Study. An estimated annual percentage change (EAPC) was calculated to assess morbidity, mortality, and DALY trends. RESULTS: The incident cases of UFs increased from 5,769,658 (95%UI, 7,634,3995–4,274,824) incidences in 1990 to 9,643,336 (95%UI, 7,178,053-12,714,741) incidences in 2017, and the age-standardized incidence rate was steady at 225.67/100,000 persons (95%UI, 167.33–298.87) in 1990 to 241.18/100,000 persons (95%UI, 179,45–318.02) in 2019. The incidence ratio in the high sociodemographic index (SDI) region showed a unimodal distribution, with peaks in 2005. Between 2009 and 2017, the age-standardized death rate of UFs declined globally, especially in low-SDI and low-middle SDI regions. In contrast with 860,619 DALYs (95%UI, 473,067-1,505,289) in 1990, the number of DALYs was 1,378,497 (95%UI, 710,915-2,475,244) in 2019, which had increased significantly, whereas the age-standardized DALY rate decreased expressively with an EAPC of −1.93 (95%CI, from −2.16 to −1.71). CONCLUSION: The global burden of UFs increased between 1990 and 2019, and the incidences and DALYs increased prominently worldwide, while the deaths from UFs had no evident growth. Lower SDI regions carried an incremental burden of UFs, while disease reduction was observed in higher SDI regions. It is high time we paid attention to the underprivileged regional quality of life and health protection. Frontiers Media S.A. 2022-11-07 /pmc/articles/PMC9676237/ /pubmed/36419793 http://dx.doi.org/10.3389/fmed.2022.1003605 Text en Copyright © 2022 Cheng, Li, Gong, Huang, Zhang and Yan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Cheng, Lin-Can Li, Hao-Yang Gong, Qin-Qin Huang, Cheng-Yang Zhang, Chao Yan, Jin-Zhu Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study |
title | Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study |
title_full | Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study |
title_fullStr | Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study |
title_full_unstemmed | Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study |
title_short | Global, regional, and national burden of uterine fibroids in the last 30 years: Estimates from the 1990 to 2019 Global Burden of Disease Study |
title_sort | global, regional, and national burden of uterine fibroids in the last 30 years: estimates from the 1990 to 2019 global burden of disease study |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676237/ https://www.ncbi.nlm.nih.gov/pubmed/36419793 http://dx.doi.org/10.3389/fmed.2022.1003605 |
work_keys_str_mv | AT chenglincan globalregionalandnationalburdenofuterinefibroidsinthelast30yearsestimatesfromthe1990to2019globalburdenofdiseasestudy AT lihaoyang globalregionalandnationalburdenofuterinefibroidsinthelast30yearsestimatesfromthe1990to2019globalburdenofdiseasestudy AT gongqinqin globalregionalandnationalburdenofuterinefibroidsinthelast30yearsestimatesfromthe1990to2019globalburdenofdiseasestudy AT huangchengyang globalregionalandnationalburdenofuterinefibroidsinthelast30yearsestimatesfromthe1990to2019globalburdenofdiseasestudy AT zhangchao globalregionalandnationalburdenofuterinefibroidsinthelast30yearsestimatesfromthe1990to2019globalburdenofdiseasestudy AT yanjinzhu globalregionalandnationalburdenofuterinefibroidsinthelast30yearsestimatesfromthe1990to2019globalburdenofdiseasestudy |