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AAV process intensification by perfusion bioreaction and integrated clarification
Adeno-associated viruses (AAVs) demand for clinical trials and approved therapeutic applications is increasing due to this vector’s overall success and potential. The high doses associated with administration strategies challenges bioprocess engineers to develop more efficient technologies and innov...
Autores principales: | Mendes, João P., Fernandes, Bárbara, Pineda, Earl, Kudugunti, Shashi, Bransby, Mike, Gantier, René, Peixoto, Cristina, Alves, Paula M., Roldão, António, Silva, Ricardo J. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676353/ https://www.ncbi.nlm.nih.gov/pubmed/36420444 http://dx.doi.org/10.3389/fbioe.2022.1020174 |
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