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HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication

Chronic hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma. However, the function and mechanism of the effect of HBV on host protein ubiquitination remain largely unknown. We aimed at characterizing whether and how HBV promotes self-replication by affecting host protein...

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Detalles Bibliográficos
Autores principales: Yuan, Sen, Xu, Jiaqi, Wang, Min, Huang, Junsong, Ma, Shuangshuang, Liu, Yang, Ke, Yujia, Zeng, Xianhuang, Wu, Kangwei, Wang, Jingwen, Tian, Xuezhang, Zheng, Dandan, Yousaf, Tanzeel, Naz, Wajeeha, Sun, Junwei, Chen, Lang, Guo, Deyin, Guo, Mingxiong, Sun, Guihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676396/
https://www.ncbi.nlm.nih.gov/pubmed/36096451
http://dx.doi.org/10.1016/j.jcmgh.2022.09.003