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Case Report: MAP2K1 K57N mutation is associated with primary resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer

BACKGROUND: We aim to identify the prevalence and the role of the MAP2K1 K57N mutation in predicting resistance to anti-EGFR agents in metastatic colorectal cancer (mCRC) patients. METHODS: We retrospectively reviewed tumor-based next generation sequencing (NGS) results from mCRC patients screened f...

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Detalles Bibliográficos
Autores principales:	Mauri, Gianluca, Patelli, Giorgio, Gori, Viviana, Lauricella, Calogero, Mussolin, Benedetta, Amatu, Alessio, Bencardino, Katia, Tosi, Federica, Bonazzina, Erica, Bonoldi, Emanuela, Bardelli, Alberto, Siena, Salvatore, Sartore-Bianchi, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676472/ https://www.ncbi.nlm.nih.gov/pubmed/36419886 http://dx.doi.org/10.3389/fonc.2022.1030232

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