A protocol for establishing a male G×E schizophrenia mouse model

Schizophrenia pathogenesis involves both genetic and environmental factors (G×E). Here, we present a protocol to prepare a schizophrenia rodent model with a specific G×E pair. We describe the breeding of Bdnf-e6−/− mice with genetic deficiency in promoter-VI-driven BDNF expression. We then detail th...

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Detalles Bibliográficos
Autores principales: Zhang, Tianyi, Li, Shangjin, Mei, Fan, You, He, Chen, Yanghui, Yang, Feng, Lu, Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676628/
https://www.ncbi.nlm.nih.gov/pubmed/36595927
http://dx.doi.org/10.1016/j.xpro.2022.101856

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