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Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities

Herbal tea is a mainstay dosage form in practically all systems of traditional medicine and widely used in modern alternative and complementary medicine. Incorporating botanical extracts into herbal tea formulations is of vital interest to manufacturers as it allows for the use of herbal ingredients...

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Autores principales: Brendler, T., Brinckmann, J. A., Daoust, M., He, H., Masé, G., Steffan, K., Williams, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676638/
https://www.ncbi.nlm.nih.gov/pubmed/36419619
http://dx.doi.org/10.3389/fphar.2022.1013340
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author Brendler, T.
Brinckmann, J. A.
Daoust, M.
He, H.
Masé, G.
Steffan, K.
Williams, M.
author_facet Brendler, T.
Brinckmann, J. A.
Daoust, M.
He, H.
Masé, G.
Steffan, K.
Williams, M.
author_sort Brendler, T.
collection PubMed
description Herbal tea is a mainstay dosage form in practically all systems of traditional medicine and widely used in modern alternative and complementary medicine. Incorporating botanical extracts into herbal tea formulations is of vital interest to manufacturers as it allows for the use of herbal ingredients that would otherwise not be suitable for the dosage form, for instance, dosing requirements, solubility in water, sensory constraints etc. Furthermore, reducing the amount of ingredients in a formula increases compliance with dosing recommendations and thus therapeutic benefit. However, formulating with botanical extracts comes with challenges, ranging from sourcing ingredients of appropriate quality, developing suitable methods for quality control with combinations of (herbal) ingredients, processing constraints such as hygroscopicity, solubility, dispersibility, homogeneity of distribution, and packaging machinability, all the way to stability required for hot-water infusion. We report on experiences with overcoming such challenges in a set of examples and provide guidance to the extract industry on how to tap into the bagged tea sector with better suited or tailor-made solutions for the formulator.
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spelling pubmed-96766382022-11-22 Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities Brendler, T. Brinckmann, J. A. Daoust, M. He, H. Masé, G. Steffan, K. Williams, M. Front Pharmacol Pharmacology Herbal tea is a mainstay dosage form in practically all systems of traditional medicine and widely used in modern alternative and complementary medicine. Incorporating botanical extracts into herbal tea formulations is of vital interest to manufacturers as it allows for the use of herbal ingredients that would otherwise not be suitable for the dosage form, for instance, dosing requirements, solubility in water, sensory constraints etc. Furthermore, reducing the amount of ingredients in a formula increases compliance with dosing recommendations and thus therapeutic benefit. However, formulating with botanical extracts comes with challenges, ranging from sourcing ingredients of appropriate quality, developing suitable methods for quality control with combinations of (herbal) ingredients, processing constraints such as hygroscopicity, solubility, dispersibility, homogeneity of distribution, and packaging machinability, all the way to stability required for hot-water infusion. We report on experiences with overcoming such challenges in a set of examples and provide guidance to the extract industry on how to tap into the bagged tea sector with better suited or tailor-made solutions for the formulator. Frontiers Media S.A. 2022-11-07 /pmc/articles/PMC9676638/ /pubmed/36419619 http://dx.doi.org/10.3389/fphar.2022.1013340 Text en Copyright © 2022 Brendler, Brinckmann, Daoust, He, Masé, Steffan and Williams. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Brendler, T.
Brinckmann, J. A.
Daoust, M.
He, H.
Masé, G.
Steffan, K.
Williams, M.
Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
title Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
title_full Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
title_fullStr Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
title_full_unstemmed Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
title_short Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
title_sort suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676638/
https://www.ncbi.nlm.nih.gov/pubmed/36419619
http://dx.doi.org/10.3389/fphar.2022.1013340
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