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Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
Herbal tea is a mainstay dosage form in practically all systems of traditional medicine and widely used in modern alternative and complementary medicine. Incorporating botanical extracts into herbal tea formulations is of vital interest to manufacturers as it allows for the use of herbal ingredients...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676638/ https://www.ncbi.nlm.nih.gov/pubmed/36419619 http://dx.doi.org/10.3389/fphar.2022.1013340 |
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author | Brendler, T. Brinckmann, J. A. Daoust, M. He, H. Masé, G. Steffan, K. Williams, M. |
author_facet | Brendler, T. Brinckmann, J. A. Daoust, M. He, H. Masé, G. Steffan, K. Williams, M. |
author_sort | Brendler, T. |
collection | PubMed |
description | Herbal tea is a mainstay dosage form in practically all systems of traditional medicine and widely used in modern alternative and complementary medicine. Incorporating botanical extracts into herbal tea formulations is of vital interest to manufacturers as it allows for the use of herbal ingredients that would otherwise not be suitable for the dosage form, for instance, dosing requirements, solubility in water, sensory constraints etc. Furthermore, reducing the amount of ingredients in a formula increases compliance with dosing recommendations and thus therapeutic benefit. However, formulating with botanical extracts comes with challenges, ranging from sourcing ingredients of appropriate quality, developing suitable methods for quality control with combinations of (herbal) ingredients, processing constraints such as hygroscopicity, solubility, dispersibility, homogeneity of distribution, and packaging machinability, all the way to stability required for hot-water infusion. We report on experiences with overcoming such challenges in a set of examples and provide guidance to the extract industry on how to tap into the bagged tea sector with better suited or tailor-made solutions for the formulator. |
format | Online Article Text |
id | pubmed-9676638 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96766382022-11-22 Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities Brendler, T. Brinckmann, J. A. Daoust, M. He, H. Masé, G. Steffan, K. Williams, M. Front Pharmacol Pharmacology Herbal tea is a mainstay dosage form in practically all systems of traditional medicine and widely used in modern alternative and complementary medicine. Incorporating botanical extracts into herbal tea formulations is of vital interest to manufacturers as it allows for the use of herbal ingredients that would otherwise not be suitable for the dosage form, for instance, dosing requirements, solubility in water, sensory constraints etc. Furthermore, reducing the amount of ingredients in a formula increases compliance with dosing recommendations and thus therapeutic benefit. However, formulating with botanical extracts comes with challenges, ranging from sourcing ingredients of appropriate quality, developing suitable methods for quality control with combinations of (herbal) ingredients, processing constraints such as hygroscopicity, solubility, dispersibility, homogeneity of distribution, and packaging machinability, all the way to stability required for hot-water infusion. We report on experiences with overcoming such challenges in a set of examples and provide guidance to the extract industry on how to tap into the bagged tea sector with better suited or tailor-made solutions for the formulator. Frontiers Media S.A. 2022-11-07 /pmc/articles/PMC9676638/ /pubmed/36419619 http://dx.doi.org/10.3389/fphar.2022.1013340 Text en Copyright © 2022 Brendler, Brinckmann, Daoust, He, Masé, Steffan and Williams. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Brendler, T. Brinckmann, J. A. Daoust, M. He, H. Masé, G. Steffan, K. Williams, M. Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
title | Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
title_full | Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
title_fullStr | Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
title_full_unstemmed | Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
title_short | Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
title_sort | suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676638/ https://www.ncbi.nlm.nih.gov/pubmed/36419619 http://dx.doi.org/10.3389/fphar.2022.1013340 |
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