PERM1 regulates energy metabolism in the heart via ERRα/PGC−1α axis

AIMS: PERM1 is a striated muscle-specific regulator of mitochondrial bioenergetics. We previously demonstrated that PERM1 is downregulated in the failing heart and that PERM1 positively regulates metabolic genes known as targets of the transcription factor ERRα and its coactivator PGC-1α in cultured...

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Detalles Bibliográficos
Autores principales: Oka, Shin-ichi, Sreedevi, Karthi, Shankar, Thirupura S., Yedla, Shreya, Arowa, Sumaita, James, Amina, Stone, Kathryn G., Olmos, Katia, Sabry, Amira D., Horiuchi, Amanda, Cawley, Keiko M., O’very, Sean A., Tong, Mingming, Byun, Jaemin, Xu, Xiaoyong, Kashyap, Sanchita, Mourad, Youssef, Vehra, Omair, Calder, Dallen, Lunde, Ty, Liu, Tong, Li, Hong, Mashchek, J. Alan, Cox, James, Saijoh, Yukio, Drakos, Stavros G., Warren, Junco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676655/
https://www.ncbi.nlm.nih.gov/pubmed/36419485
http://dx.doi.org/10.3389/fcvm.2022.1033457

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