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Adefovir dipivoxil inhibits APL progression through degradation of the oncoprotein PML-RARA
Acute promyelocytic leukemia (APL) is highly aggressive and is frequently associated with disseminated intravascular coagulation and high early death rates. Although all-trans retinoic acid (RA) induces complete remission in a high proportion of patients with APL, there are limited treatments for AP...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676767/ https://www.ncbi.nlm.nih.gov/pubmed/36404334 http://dx.doi.org/10.1186/s40164-022-00355-1 |