Cargando…

Adefovir dipivoxil inhibits APL progression through degradation of the oncoprotein PML-RARA

Acute promyelocytic leukemia (APL) is highly aggressive and is frequently associated with disseminated intravascular coagulation and high early death rates. Although all-trans retinoic acid (RA) induces complete remission in a high proportion of patients with APL, there are limited treatments for AP...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Xubo, Kong, Piaoping, Yu, Teng, Xiao, Xibin, Wang, Lin, Sang, Yiwen, Li, Xiang, Zhang, Bin, Tao, Zhihua, Liu, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676767/
https://www.ncbi.nlm.nih.gov/pubmed/36404334
http://dx.doi.org/10.1186/s40164-022-00355-1