Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations

BACKGROUND AND OBJECTIVES: Prediction of antimicrobial target-site pharmacokinetics is of relevance to optimize treatment with antimicrobial agents. A physiologically based pharmacokinetic (PBPK) model framework was developed for prediction of pulmonary pharmacokinetics, including key pulmonary infe...

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Detalles Bibliográficos
Autores principales: Aulin, Linda B. S., Tandar, Sebastian T., van Zijp, Torben, van Ballegooie, Etienne, van der Graaf, Piet H., Saleh, Mohammed A. A., Välitalo, Pyry, van Hasselt, J. G. Coen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676785/
https://www.ncbi.nlm.nih.gov/pubmed/36401151
http://dx.doi.org/10.1007/s40262-022-01186-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676785/
https://www.ncbi.nlm.nih.gov/pubmed/36401151
http://dx.doi.org/10.1007/s40262-022-01186-3

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