Cargando…

Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations

BACKGROUND AND OBJECTIVES: Prediction of antimicrobial target-site pharmacokinetics is of relevance to optimize treatment with antimicrobial agents. A physiologically based pharmacokinetic (PBPK) model framework was developed for prediction of pulmonary pharmacokinetics, including key pulmonary infe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aulin, Linda B. S., Tandar, Sebastian T., van Zijp, Torben, van Ballegooie, Etienne, van der Graaf, Piet H., Saleh, Mohammed A. A., Välitalo, Pyry, van Hasselt, J. G. Coen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676785/ https://www.ncbi.nlm.nih.gov/pubmed/36401151 http://dx.doi.org/10.1007/s40262-022-01186-3

Ejemplares similares

Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans
por: Aulin, Linda B. S., et al.
Publicado: (2018)

Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling
por: Mehta, Krina, et al.
Publicado: (2023)

Predicting Drug Concentration‐Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically‐Based Pharmacokinetic Model
por: Yamamoto, Yumi, et al.
Publicado: (2017)

Design principles of collateral sensitivity-based dosing strategies
por: Aulin, Linda B. S., et al.
Publicado: (2021)

Biomarker‐Guided Individualization of Antibiotic Therapy
por: Aulin, Linda B.S., et al.
Publicado: (2021)

Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism
por: Liu, Feiyan, et al.
Publicado: (2023)

Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia
por: Aulin, Linda B. S., et al.
Publicado: (2022)

Population Pharmacokinetics of Dexmedetomidine in Critically Ill Patients
por: Välitalo, Pyry Antti, et al.
Publicado: (2013)

Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations
por: Liu, Feiyan, et al.
Publicado: (2022)

Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution
por: Liakopoulos, Apostolos, et al.
Publicado: (2022)

Pharmacometric estimation methods for aggregate data, including data simulated from other pharmacometric models
por: Välitalo, Pyry Antti Juhana
Publicado: (2021)

Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide
por: de Hoogd, Sjoerd, et al.
Publicado: (2017)

A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis
por: Liu, Feiyan, et al.
Publicado: (2022)

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs
por: Janssen, J. M., et al.
Publicado: (2023)

Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors
por: Centanni, Maddalena, et al.
Publicado: (2019)

The Influence of Normalization Weight in Population Pharmacokinetic Covariate Models
por: Goulooze, Sebastiaan C., et al.
Publicado: (2018)

Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling
por: Litjens, Carlijn H. C., et al.
Publicado: (2021)

A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations
por: Yamamoto, Yumi, et al.
Publicado: (2016)

Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy
por: van Hasselt, J. G. Coen, et al.
Publicado: (2014)

Corrigendum to “Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy”
por: van Hasselt, J. G. Coen, et al.
Publicado: (2015)

Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments
por: Calvier, Elisa A. M., et al.
Publicado: (2018)

Health Services: A Mixed Methods Assessment of Canadian Cancer Patient Education Materials Related to the 2019 Novel Coronavirus
por: van Ballegooie, Courtney, et al.
Publicado: (2021)

Assessment of the Readability of Web-Based Patient Education Material From Major Canadian Pediatric Associations: Cross-sectional Study
por: Man, Alice, et al.
Publicado: (2022)

Assessment of online patient education material for eye cancers: A cross-sectional study
por: van Ballegooie, Courtney, et al.
Publicado: (2023)

Evaluation of a Cardiovascular Systems Model for Design and Analysis of Hemodynamic Safety Studies
por: Fu, Yu, et al.
Publicado: (2023)

Semiphysiologically based pharmacokinetic model for midazolam and CYP3A mediated metabolite 1‐OH‐midazolam in morbidly obese and weight loss surgery patients
por: Brill, MJE, et al.
Publicado: (2015)

Modelling concentrations of antimicrobial drugs: comparative pharmacokinetics of cephalosporin antimicrobials and accuracy of allometric scaling in food-producing and companion animals
por: Taverne, Femke J., et al.
Publicado: (2016)

A Physiology-Based Pharmacokinetic Framework to Support Drug Development and Dose Precision During Therapeutic Hypothermia in Neonates
por: Smits, Anne, et al.
Publicado: (2020)

Crowdsourced Asparagus Urinary Odor Population Kinetics
por: Ramamoorthy, Anuradha, et al.
Publicado: (2017)

Assessment of the Readability and Quality of Online Patient Education Material for Chronic Medical Conditions
por: Hoang, Peter Minh, et al.
Publicado: (2022)

A combined physiologically‐based pharmacokinetic and quantitative systems pharmacology model for modeling amyloid aggregation in Alzheimer's disease
por: Geerts, Hugo, et al.
Publicado: (2023)

A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables
por: Fu, Yu, et al.
Publicado: (2022)

Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen
por: van Rongen, Anne, et al.
Publicado: (2016)

Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults
por: van Rongen, Anne, et al.
Publicado: (2017)

A Comprehensive Framework for Physiologically‐Based Pharmacokinetic Modeling in Matlab
por: Stader, Felix, et al.
Publicado: (2019)

Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae
por: van Wijk, Rob C., et al.
Publicado: (2019)

Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients
por: Guo, Tingjie, et al.
Publicado: (2022)

Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy
por: Kantae, Vasudev, et al.
Publicado: (2016)

Spatially Specific Liposomal Cancer Therapy Triggered by Clinical External Sources of Energy
por: van Ballegooie, Courtney, et al.
Publicado: (2019)

Assessing the Functional Accessibility, Actionability, and Quality of Patient Education Materials from Canadian Cancer Agencies
por: van Ballegooie, Courtney, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qgthcuffrgfch55ukc0ecshi79