Follicular regulatory T cells eliminate HIV-1-infected follicular helper T cells in an IL-2 concentration dependent manner

Follicular helper CD4(+) T cells (TFH) are highly permissive to HIV and major foci of virus expression in both untreated and treated infection. Follicular regulatory CD4(+) T cells (TFR) limit TFH numbers and function in vitro and in vivo. We evaluated the hypothesis that TFR suppress HIV replicatio...

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Detalles Bibliográficos
Autores principales: Ollerton, Matthew T., Folkvord, Joy M., La Mantia, Andriana, Parry, David A., Meditz, Amie L., McCarter, Martin D., D’Aquila, Richard T., Connick, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676968/
https://www.ncbi.nlm.nih.gov/pubmed/36420277
http://dx.doi.org/10.3389/fimmu.2022.878273

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