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Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients

OBJECTIVE: Early and accurate diagnosis of acute respiratory infections is important because these diseases negatively affect public health and can lead to loss of workforce and an increase in health expenditures. In this study, we aimed to determine the respiration panel multiplex polymerase chain...

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Autores principales: Zeytinli, Ulku Oral, Durmuslu, Ayca Ozer, Aslan, Ferhat Gurkan, Dincer, Solen Daldaban, Eker, Pinar, Aksaray, Sebahat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677051/
https://www.ncbi.nlm.nih.gov/pubmed/36447578
http://dx.doi.org/10.14744/nci.2021.28034
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author Zeytinli, Ulku Oral
Durmuslu, Ayca Ozer
Aslan, Ferhat Gurkan
Dincer, Solen Daldaban
Eker, Pinar
Aksaray, Sebahat
author_facet Zeytinli, Ulku Oral
Durmuslu, Ayca Ozer
Aslan, Ferhat Gurkan
Dincer, Solen Daldaban
Eker, Pinar
Aksaray, Sebahat
author_sort Zeytinli, Ulku Oral
collection PubMed
description OBJECTIVE: Early and accurate diagnosis of acute respiratory infections is important because these diseases negatively affect public health and can lead to loss of workforce and an increase in health expenditures. In this study, we aimed to determine the respiration panel multiplex polymerase chain reaction (PCR) test results and seasonal distribution in our region. METHODS: Three thousand and seventy-four patients samples multiplex PCR (Anatolia, Bosphore(®) Respiratory Pathogens Panel Kit v1) test results, which were sent to our laboratory, from 13 hospitals in our region between January 2018 and December 2018, were evaluated retrospectively. RESULTS: A total of 3074 patients samples, 1465 (48%) were positive and 1609 (52%) were negative test results. The most common factors were rhinovirus 30.2%, influenza A 23.1%, and respiratory syncytial virus (RSV) A/B 19.1%, respectively. When the distribution of these three most common viruses by months is examined, the most frequent months were determined as June for rhinovirus, November for influenza A, and February for RSV A/B. In the period between October and February, there was a significant increase in the positivity level of viral factors. CONCLUSION: The use of molecular methods in the diagnosis of respiratory infections will prevent unnecessary use of antibiotics and ensure correct and rapid treatment.
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spelling pubmed-96770512022-11-28 Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients Zeytinli, Ulku Oral Durmuslu, Ayca Ozer Aslan, Ferhat Gurkan Dincer, Solen Daldaban Eker, Pinar Aksaray, Sebahat North Clin Istanb Original Article OBJECTIVE: Early and accurate diagnosis of acute respiratory infections is important because these diseases negatively affect public health and can lead to loss of workforce and an increase in health expenditures. In this study, we aimed to determine the respiration panel multiplex polymerase chain reaction (PCR) test results and seasonal distribution in our region. METHODS: Three thousand and seventy-four patients samples multiplex PCR (Anatolia, Bosphore(®) Respiratory Pathogens Panel Kit v1) test results, which were sent to our laboratory, from 13 hospitals in our region between January 2018 and December 2018, were evaluated retrospectively. RESULTS: A total of 3074 patients samples, 1465 (48%) were positive and 1609 (52%) were negative test results. The most common factors were rhinovirus 30.2%, influenza A 23.1%, and respiratory syncytial virus (RSV) A/B 19.1%, respectively. When the distribution of these three most common viruses by months is examined, the most frequent months were determined as June for rhinovirus, November for influenza A, and February for RSV A/B. In the period between October and February, there was a significant increase in the positivity level of viral factors. CONCLUSION: The use of molecular methods in the diagnosis of respiratory infections will prevent unnecessary use of antibiotics and ensure correct and rapid treatment. Kare Publishing 2022-10-26 /pmc/articles/PMC9677051/ /pubmed/36447578 http://dx.doi.org/10.14744/nci.2021.28034 Text en © Copyright 2022 by Istanbul Provincial Directorate of Health https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Original Article
Zeytinli, Ulku Oral
Durmuslu, Ayca Ozer
Aslan, Ferhat Gurkan
Dincer, Solen Daldaban
Eker, Pinar
Aksaray, Sebahat
Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients
title Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients
title_full Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients
title_fullStr Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients
title_full_unstemmed Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients
title_short Distribution of respiratory viruses: Evaluation of multiplex PCR results of 3074 patients
title_sort distribution of respiratory viruses: evaluation of multiplex pcr results of 3074 patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677051/
https://www.ncbi.nlm.nih.gov/pubmed/36447578
http://dx.doi.org/10.14744/nci.2021.28034
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