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Hydrophobicity identifies false positives and false negatives in peptide-MHC binding

Major Histocompability Complex (MHC) Class I molecules allow cells to present foreign and endogenous peptides to T-Cells so that cells infected by pathogens can be identified and killed. Neural networks tools such as NetMHC-4.0 and NetMHCpan-4.1 are used to predict whether peptides will bind to vari...

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Detalles Bibliográficos
Autores principales:	Solanki, Arnav, Riedel, Marc, Cornette, James, Udell, Julia, Vasmatzis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677119/ https://www.ncbi.nlm.nih.gov/pubmed/36419888 http://dx.doi.org/10.3389/fonc.2022.1034810

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