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Recombinant protein condensation inside E. coli enables the development of building blocks for bioinspired materials engineering – Biomimetic spider silk protein as a case study
Recombinant expression of proteins destined to form biological materials often results in poor production yields or loss of their function due to premature aggregation. Recently, liquid-liquid phase separation has been proposed as a mechanism to control protein solubility during expression and accum...
Autores principales: | Gabryelczyk, Bartosz, Sammalisto, Fred-Eric, Gandier, Julie-Anne, Feng, Jianhui, Beaune, Grégory, Timonen, Jaakko V.I., Linder, Markus B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677211/ https://www.ncbi.nlm.nih.gov/pubmed/36420055 http://dx.doi.org/10.1016/j.mtbio.2022.100492 |
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