Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

BACKGROUND: Mammalian sperm maturation in the epididymis is mainly modulated by exosomes that are secreted into the epididymal lumen from epididymal epithelial cells (EECs). Exposure to oxidative stress (OS) resulting from being fed a high fat diet (HFD) reduces sperm fertility, which is one of the...

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Detalles Bibliográficos
Autores principales: Li, Yangyang, Zhao, Wenzhen, Fu, Rong, Ma, Zhuoyao, Hu, Yanqin, Liu, Yue, Ding, Zhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677646/
https://www.ncbi.nlm.nih.gov/pubmed/36411474
http://dx.doi.org/10.1186/s12958-022-01031-z

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