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The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code

A brief description of why and for which purposes the Prospective Lynch Syndrome Database was established, the principles and design, and the main classes of results are given. Data input is assumption-free input enabling validation of paradigms used to explain the results. The design is considering...

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Autor principal: Møller, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677689/
https://www.ncbi.nlm.nih.gov/pubmed/36411472
http://dx.doi.org/10.1186/s13053-022-00243-z
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author_facet Møller, Pål
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description A brief description of why and for which purposes the Prospective Lynch Syndrome Database was established, the principles and design, and the main classes of results are given. Data input is assumption-free input enabling validation of paradigms used to explain the results. The design is considering cancer/age as discrete events to occur or not in a time dimension in a closed room compliant with population genetic paradigms and last centuries developing paradigms of interpreting discrete events reflecting conditional and/or co-occurring stochastic probabilities. Which may be in contrast to the paradigm that any observed event has a cause. The results may indicate that some current paradigms on carcinogenesis should be reconsidered. The complete analytic code in MySQL© syntax together with a flowchart illustrating how the different pieces of codes interrelate are included as supplementary files, enabling third parties to use or modify the code to examine prospectively observed events in their own activities when referring to this report as the source. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13053-022-00243-z.
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spelling pubmed-96776892022-11-22 The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code Møller, Pål Hered Cancer Clin Pract Editorial A brief description of why and for which purposes the Prospective Lynch Syndrome Database was established, the principles and design, and the main classes of results are given. Data input is assumption-free input enabling validation of paradigms used to explain the results. The design is considering cancer/age as discrete events to occur or not in a time dimension in a closed room compliant with population genetic paradigms and last centuries developing paradigms of interpreting discrete events reflecting conditional and/or co-occurring stochastic probabilities. Which may be in contrast to the paradigm that any observed event has a cause. The results may indicate that some current paradigms on carcinogenesis should be reconsidered. The complete analytic code in MySQL© syntax together with a flowchart illustrating how the different pieces of codes interrelate are included as supplementary files, enabling third parties to use or modify the code to examine prospectively observed events in their own activities when referring to this report as the source. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13053-022-00243-z. BioMed Central 2022-11-21 /pmc/articles/PMC9677689/ /pubmed/36411472 http://dx.doi.org/10.1186/s13053-022-00243-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Editorial
Møller, Pål
The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
title The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
title_full The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
title_fullStr The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
title_full_unstemmed The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
title_short The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
title_sort prospective lynch syndrome database: background, design, main results and complete mysql code
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677689/
https://www.ncbi.nlm.nih.gov/pubmed/36411472
http://dx.doi.org/10.1186/s13053-022-00243-z
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