Tumor microenvironment-associated lactate metabolism regulates the prognosis and precise checkpoint immunotherapy outcomes of patients with lung adenocarcinoma

BACKGROUND: Despite the wide clinical application of checkpoint inhibitor immunotherapy in lung adenocarcinoma, its limited benefit to patients remains puzzling to researchers. One of the mechanisms of immunotherapy resistance may be the dysregulation of lactate metabolism in the immunosuppressive t...

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Detalles Bibliográficos
Autores principales: Qiu, Song, Wang, Ying, Rao, Hui, Que, Qiuyang, Wu, Yanyang, Zhu, Rui, Feng, Xiaofei, Chi, Jun, Lai, Weiling, Sun, Yihang, Xiao, Qi, Shi, Huaqiu, Xiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677690/
https://www.ncbi.nlm.nih.gov/pubmed/36411477
http://dx.doi.org/10.1186/s40001-022-00895-6

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