Cargando…

FGF12 is a novel component of the nucleolar NOLC1/TCOF1 ribosome biogenesis complex

Among the FGF proteins, the least characterized superfamily is the group of fibroblast growth factor homologous factors (FHFs). To date, the main role of FHFs has been primarily seen in the modulation of voltage-gated ion channels, but a full picture of the function of FHFs inside the cell is far fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sochacka, Martyna, Karelus, Radoslaw, Opalinski, Lukasz, Krowarsch, Daniel, Biadun, Martyna, Otlewski, Jacek, Zakrzewska, Malgorzata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677703/ https://www.ncbi.nlm.nih.gov/pubmed/36411431 http://dx.doi.org/10.1186/s12964-022-01000-4

Ejemplares similares

Low Stability of Integrin-Binding Deficient Mutant of FGF1 Restricts Its Biological Activity
por: Szlachcic, Anna, et al.
Publicado: (2019)

FGF1 protects FGFR1-overexpressing cancer cells against drugs targeting tubulin polymerization by activating AKT via two independent mechanisms
por: Szymczyk, Jakub, et al.
Publicado: (2022)

FHF1 is a bona fide fibroblast growth factor that activates cellular signaling in FGFR-dependent manner
por: Sochacka, Martyna, et al.
Publicado: (2020)

Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
por: Lampart, Agata, et al.
Publicado: (2023)

High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1
por: Opaliński, Łukasz, et al.
Publicado: (2018)

Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity
por: Opaliński, Łukasz, et al.
Publicado: (2017)

Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
por: Zakrzewska, Malgorzata, et al.
Publicado: (2019)

FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1
por: Świderska, Karolina Weronika, et al.
Publicado: (2018)

The cytotoxic conjugate of highly internalizing tetravalent antibody for targeting FGFR1-overproducing cancer cells
por: Poźniak, Marta, et al.
Publicado: (2021)

Increased Protein Stability of FGF1 Can Compensate for Its Reduced Affinity for Heparin
por: Zakrzewska, Malgorzata, et al.
Publicado: (2009)

Nucleolar and coiled-body phosphoprotein 1 (NOLC1) regulates the nucleolar retention of TRF2
por: Yuan, Fuwen, et al.
Publicado: (2017)

Genetic mutations in ribosomal biogenesis gene TCOF1 identified in human neural tube defects
por: Wang, Fang, et al.
Publicado: (2023)

FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance
por: Szymczyk, Jakub, et al.
Publicado: (2021)

FGF1 Fusions with the Fc Fragment of IgG1 for the Assembly of GFPpolygons-Mediated Multivalent Complexes Recognizing FGFRs
por: Poźniak, Marta, et al.
Publicado: (2021)

The oncogenic role of treacle ribosome biogenesis factor 1 (TCOF1) in human tumors: a pan-cancer analysis
por: Gu, Wei, et al.
Publicado: (2022)

Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
por: Krzyscik, Mateusz Adam, et al.
Publicado: (2017)

Receptor clustering by a precise set of extracellular galectins initiates FGFR signaling
por: Zukowska, Dominika, et al.
Publicado: (2023)

Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling
por: Gedaj, Aleksandra, et al.
Publicado: (2023)

Correction: Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling
por: Gedaj, Aleksandra, et al.
Publicado: (2023)

Nucleolar RNA polymerase II drives ribosome biogenesis
por: Abraham, Karan J., et al.
Publicado: (2020)

Stable Fibroblast Growth Factor 2 Dimers with High Pro-Survival and Mitogenic Potential
por: Nawrocka, Daria, et al.
Publicado: (2020)

Intrinsically Fluorescent Oligomeric Cytotoxic Conjugates Toxic for FGFR1-Overproducing Cancers
por: Porębska, Natalia, et al.
Publicado: (2021)

FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
por: Jendryczko, Karolina, et al.
Publicado: (2020)

Identification of new FGF1 binding partners—Implications for its intracellular function
por: Bober, Joanna, et al.
Publicado: (2016)

Targeting Cellular Trafficking of Fibroblast Growth Factor Receptors as a Strategy for Selective Cancer Treatment
por: Porębska, Natalia, et al.
Publicado: (2018)

Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins
por: Kucińska, Marika, et al.
Publicado: (2019)

Nucleolar TFIIE plays a role in ribosomal biogenesis and performance
por: Phan, Tamara, et al.
Publicado: (2021)

FGF1 Protects MCF-7 Cells against Taltobulin through Both the MEKs/ERKs and PI3K/AKT Signaling Pathway
por: Szymczyk, Jakub, et al.
Publicado: (2023)

Specific Antibody Fragment Ligand Traps Blocking FGF1 Activity
por: Chudzian, Julia, et al.
Publicado: (2018)

Site-Specific, Stoichiometric-Controlled, PEGylated Conjugates of Fibroblast Growth Factor 2 (FGF2) with Hydrophilic Auristatin Y for Highly Selective Killing of Cancer Cells Overproducing Fibroblast Growth Factor Receptor 1 (FGFR1)
por: Krzyscik, Mateusz Adam, et al.
Publicado: (2020)

Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number
por: Farley-Barnes, Katherine I., et al.
Publicado: (2018)

FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation
por: Szlachcic, Anna, et al.
Publicado: (2012)

N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope
por: Gregorczyk, Paulina, et al.
Publicado: (2023)

Insulin Receptor Substrate-1 Associates with Small Nucleolar RNA Which Contributes to Ribosome Biogenesis
por: Ozoe, Atsufumi, et al.
Publicado: (2014)

Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins
por: Latko, Marta, et al.
Publicado: (2019)

The 5S RNP Couples p53 Homeostasis to Ribosome Biogenesis and Nucleolar Stress
por: Sloan, Katherine E., et al.
Publicado: (2013)

Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis
por: Gueiderikh, Anna, et al.
Publicado: (2021)

Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
por: Lampart, Agata, et al.
Publicado: (2022)

Nucleolin Regulates Phosphorylation and Nuclear Export of Fibroblast Growth Factor 1 (FGF1)
por: Sletten, Torunn, et al.
Publicado: (2014)

Nucleolar Components Involved in Ribosome Biogenesis Cycle between the Nucleolus and Nucleoplasm in Interphase Cells
por: Chen, Danyang, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_k2m2ddnnenj71j8fuqs2p4d800