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Androgen Excess Increases Food Intake in a Rat Polycystic Ovary Syndrome Model by Downregulating Hypothalamus Insulin and Leptin Signaling Pathways Preceding Weight Gain

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder characterized by high androgen levels. The aim of this study was to evaluate the effects of hyperandrogenism on the hypothalamus and subsequently on the food intake and obesity in females. METHODS: A dihydro...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Xu, Yu-Chen, Cui, Yu-Gui, Jiang, Shi-Wen, Diao, Fei-Yang, Liu, Jia-Yin, Ma, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677863/
https://www.ncbi.nlm.nih.gov/pubmed/34847556
http://dx.doi.org/10.1159/000521236