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Androgen Excess Increases Food Intake in a Rat Polycystic Ovary Syndrome Model by Downregulating Hypothalamus Insulin and Leptin Signaling Pathways Preceding Weight Gain
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder characterized by high androgen levels. The aim of this study was to evaluate the effects of hyperandrogenism on the hypothalamus and subsequently on the food intake and obesity in females. METHODS: A dihydro...
Autores principales: | Liu, Ying, Xu, Yu-Chen, Cui, Yu-Gui, Jiang, Shi-Wen, Diao, Fei-Yang, Liu, Jia-Yin, Ma, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677863/ https://www.ncbi.nlm.nih.gov/pubmed/34847556 http://dx.doi.org/10.1159/000521236 |
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