Skin Treatment with Detergent Induces Dermatitis with H1-Antihistamine-Refractory Itch and Upregulates IL-4 and Th17/Th22 Cytokine Gene Expression in C57BL/6 Mice

INTRODUCTION: Repeated skin contact to detergents causes chronic irritant contact dermatitis (ICD) associated with itch sensation and eczema. However, the mechanisms of detergent-induced ICD are poorly understood. Here, we established a new murine model of detergent-induced ICD with H1-antihistamine...

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Detalles Bibliográficos
Autores principales: Masutani, Yurie, Takai, Toshiro, Kamijo, Seiji, Kimitsu, Toru, Yoshimura, Tomoko, Ichikawa, Saori, Shimizu, Saya, Ogawa, Takasuke, Takada, Keiko, Tominaga, Mitsutoshi, Suto, Hajime, Takamori, Kenji, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Experimental Allergy − Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677871/
https://www.ncbi.nlm.nih.gov/pubmed/35933977
http://dx.doi.org/10.1159/000525656

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