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Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria
BACKGROUND: Broad spectrum antibiotics are often used for the prophylaxis of infectious endocarditis and treatment of odontogenic infections, but there are limited data related to antibiotic use and adherence to prescription guidelines. METHODS: Data from patients with tooth extraction between 2014...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677908/ https://www.ncbi.nlm.nih.gov/pubmed/36404324 http://dx.doi.org/10.1186/s12903-022-02556-w |
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author | Sheikh Rezaei, Safoura Litschauer, Brigitte Anderle, Karolina Maurer, Stephanie Beyers, Patrick Jan Reichardt, Berthold Wolzt, Michael |
author_facet | Sheikh Rezaei, Safoura Litschauer, Brigitte Anderle, Karolina Maurer, Stephanie Beyers, Patrick Jan Reichardt, Berthold Wolzt, Michael |
author_sort | Sheikh Rezaei, Safoura |
collection | PubMed |
description | BACKGROUND: Broad spectrum antibiotics are often used for the prophylaxis of infectious endocarditis and treatment of odontogenic infections, but there are limited data related to antibiotic use and adherence to prescription guidelines. METHODS: Data from patients with tooth extraction between 2014 and 2018 were selected from a database of a regional health insurance fund. We created three data sets, one based on all tooth extractions, one on multiple teeth extractions, and one including only single tooth extraction. After data collection, descriptive analysis was carried out. The differences in prescription pattern of antibiotic medicine were tested by χ(2) test, Student´s t-test or ANOVA. RESULTS: From 43,863 patients with tooth extraction, 53% were female, and 3,983 patients (9.1%) filled a prescription for antibiotic medicine. From 43,863 patients, 157 patients (0.4%) had endocarditis risk, but only 8 patients of these (5.1%) filled an antibiotic prescription. In total, 9,234 patients had multiple and 34,437 patients had only one tooth extraction. Patients with more than one tooth extraction received more often antibiotic treatment (10.7%) compared to those with single tooth extractions (χ(2) = 36; p < 0,001). Patients with more than one tooth extraction were older, however, younger patients received antibiotics more frequently (t = 28,774, p = 0.001). There was no relationship with endocarditis risk status. Clindamycin and amoxicillin/clavulanic acid were the most frequently prescribed antibiotic medicines. CONCLUSIONS: In this retrospective cohort study, dentists did not discriminate prophylactic antibiotic prescription with regard to endocarditis risk status. A factor influencing prescribing behaviour of antibiotic medicines was the number of extracted teeth. |
format | Online Article Text |
id | pubmed-9677908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-96779082022-11-22 Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria Sheikh Rezaei, Safoura Litschauer, Brigitte Anderle, Karolina Maurer, Stephanie Beyers, Patrick Jan Reichardt, Berthold Wolzt, Michael BMC Oral Health Research BACKGROUND: Broad spectrum antibiotics are often used for the prophylaxis of infectious endocarditis and treatment of odontogenic infections, but there are limited data related to antibiotic use and adherence to prescription guidelines. METHODS: Data from patients with tooth extraction between 2014 and 2018 were selected from a database of a regional health insurance fund. We created three data sets, one based on all tooth extractions, one on multiple teeth extractions, and one including only single tooth extraction. After data collection, descriptive analysis was carried out. The differences in prescription pattern of antibiotic medicine were tested by χ(2) test, Student´s t-test or ANOVA. RESULTS: From 43,863 patients with tooth extraction, 53% were female, and 3,983 patients (9.1%) filled a prescription for antibiotic medicine. From 43,863 patients, 157 patients (0.4%) had endocarditis risk, but only 8 patients of these (5.1%) filled an antibiotic prescription. In total, 9,234 patients had multiple and 34,437 patients had only one tooth extraction. Patients with more than one tooth extraction received more often antibiotic treatment (10.7%) compared to those with single tooth extractions (χ(2) = 36; p < 0,001). Patients with more than one tooth extraction were older, however, younger patients received antibiotics more frequently (t = 28,774, p = 0.001). There was no relationship with endocarditis risk status. Clindamycin and amoxicillin/clavulanic acid were the most frequently prescribed antibiotic medicines. CONCLUSIONS: In this retrospective cohort study, dentists did not discriminate prophylactic antibiotic prescription with regard to endocarditis risk status. A factor influencing prescribing behaviour of antibiotic medicines was the number of extracted teeth. BioMed Central 2022-11-20 /pmc/articles/PMC9677908/ /pubmed/36404324 http://dx.doi.org/10.1186/s12903-022-02556-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Sheikh Rezaei, Safoura Litschauer, Brigitte Anderle, Karolina Maurer, Stephanie Beyers, Patrick Jan Reichardt, Berthold Wolzt, Michael Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria |
title | Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria |
title_full | Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria |
title_fullStr | Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria |
title_full_unstemmed | Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria |
title_short | Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria |
title_sort | antibiotic prescription after tooth extraction in adults: a retrospective cohort study in austria |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677908/ https://www.ncbi.nlm.nih.gov/pubmed/36404324 http://dx.doi.org/10.1186/s12903-022-02556-w |
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