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The Sphingosine Kinase 2 Inhibitor Opaganib Protects Against Acute Kidney Injury in Mice

INTRODUCTION: Acute kidney injury (AKI) is a common multifactorial adverse effect of surgery, circulatory obstruction, sepsis or drug/toxin exposure that often results in morbidity and mortality. Sphingolipid metabolism is a critical regulator of cell survival and pathologic inflammation processes i...

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Detalles Bibliográficos
Autores principales:	Maines, Lynn W, Green, Cecelia L, Keller, Staci N, Fitzpatrick, Leo R, Smith, Charles D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677921/ https://www.ncbi.nlm.nih.gov/pubmed/36420520 http://dx.doi.org/10.2147/IJNRD.S386396

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