Germline mutations in penetrant cancer predisposition genes are rare in men with prostate cancer selecting active surveillance

BACKGROUND: Pathogenic germline mutations in several rare penetrant cancer predisposition genes are associated with an increased risk of aggressive prostate cancer (PC). Our objectives were to determine the prevalence of pathogenic germline mutations in men with low‐risk PC on active surveillance, a...

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Detalles Bibliográficos
Autores principales: Brady, Lauren, Newcomb, Lisa F., Zhu, Kehao, Zheng, Yingye, Boyer, Hilary, Sarkar, Navonil De, McKenney, Jesse K., Brooks, James D., Carroll, Peter R., Dash, Atreya, Ellis, William J., Filson, Christopher P., Gleave, Martin E., Liss, Michael A., Martin, Frances, Morgan, Todd M., Thompson, Ian M., Wagner, Andrew A., Pritchard, Colin C., Lin, Daniel W., Nelson, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678104/
https://www.ncbi.nlm.nih.gov/pubmed/35467778
http://dx.doi.org/10.1002/cam4.4778

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