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Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer

Disseminated tuberculosis (TB) can mimic metastatic disease because of its multi-organ involvement (including bones), which can make the diagnosis much more complicated. Tracheoesophageal fistula is a very uncommon manifestation of TB, as is multifocal skeletal TB. There are reports of TB presenting...

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Autores principales: Subramony, Hariharan, Hegde, Manjunatha Gajanana, Raghavan, Balagurunathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678121/
https://www.ncbi.nlm.nih.gov/pubmed/36415840
http://dx.doi.org/10.12890/2022_003624
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author Subramony, Hariharan
Hegde, Manjunatha Gajanana
Raghavan, Balagurunathan
author_facet Subramony, Hariharan
Hegde, Manjunatha Gajanana
Raghavan, Balagurunathan
author_sort Subramony, Hariharan
collection PubMed
description Disseminated tuberculosis (TB) can mimic metastatic disease because of its multi-organ involvement (including bones), which can make the diagnosis much more complicated. Tracheoesophageal fistula is a very uncommon manifestation of TB, as is multifocal skeletal TB. There are reports of TB presenting either as multifocal skeletal TB or as tracheoesophageal fistulae, but we could not find any case reports describing both of these entities in a single patient and essentially mimicking a metastatic oesophageal neoplasm. However, we here describe one such case, which was managed medically. LEARNING POINTS: Disseminated tuberculosis (TB) can involve any system and may mimic many conditions. Tracheoesophageal fistula secondary to TB and multi-focal skeletal TB are both rare individually, with their co-occurrence being even more uncommon. Diagnosing and managing TB in endemic areas can be complex and challenging; the use of histopathology and molecular techniques prior to treatment is very important.
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spelling pubmed-96781212022-11-21 Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer Subramony, Hariharan Hegde, Manjunatha Gajanana Raghavan, Balagurunathan Eur J Case Rep Intern Med Articles Disseminated tuberculosis (TB) can mimic metastatic disease because of its multi-organ involvement (including bones), which can make the diagnosis much more complicated. Tracheoesophageal fistula is a very uncommon manifestation of TB, as is multifocal skeletal TB. There are reports of TB presenting either as multifocal skeletal TB or as tracheoesophageal fistulae, but we could not find any case reports describing both of these entities in a single patient and essentially mimicking a metastatic oesophageal neoplasm. However, we here describe one such case, which was managed medically. LEARNING POINTS: Disseminated tuberculosis (TB) can involve any system and may mimic many conditions. Tracheoesophageal fistula secondary to TB and multi-focal skeletal TB are both rare individually, with their co-occurrence being even more uncommon. Diagnosing and managing TB in endemic areas can be complex and challenging; the use of histopathology and molecular techniques prior to treatment is very important. SMC Media Srl 2022-10-24 /pmc/articles/PMC9678121/ /pubmed/36415840 http://dx.doi.org/10.12890/2022_003624 Text en © EFIM 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Articles
Subramony, Hariharan
Hegde, Manjunatha Gajanana
Raghavan, Balagurunathan
Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer
title Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer
title_full Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer
title_fullStr Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer
title_full_unstemmed Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer
title_short Tuberculosis, A Great Masquerader: A Case Report of Disseminated Multifocal Skeletal TB and Tracheoesophageal Fistulae Mimicking Metastatic Cancer
title_sort tuberculosis, a great masquerader: a case report of disseminated multifocal skeletal tb and tracheoesophageal fistulae mimicking metastatic cancer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678121/
https://www.ncbi.nlm.nih.gov/pubmed/36415840
http://dx.doi.org/10.12890/2022_003624
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