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SV-AUC as a stability-indicating method for the characterization of mRNA-LNPs

During the SARS-CoV2 pandemic mRNA vaccines in the form of lipid nanoparticles (LNPs) containing the mRNA, have set the stage for a new area of vaccines. Analytical methods to quantify changes in size and structure of LNPs are crucial, as changes in these parameters could have implications for poten...

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Detalles Bibliográficos
Autores principales: Thaller, Anian, Schmauder, Lukas, Frieß, Wolfgang, Winter, Gerhard, Menzen, Tim, Hawe, Andrea, Richter, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678208/
https://www.ncbi.nlm.nih.gov/pubmed/36410586
http://dx.doi.org/10.1016/j.ejpb.2022.11.014

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