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SV-AUC as a stability-indicating method for the characterization of mRNA-LNPs
During the SARS-CoV2 pandemic mRNA vaccines in the form of lipid nanoparticles (LNPs) containing the mRNA, have set the stage for a new area of vaccines. Analytical methods to quantify changes in size and structure of LNPs are crucial, as changes in these parameters could have implications for poten...
Autores principales: | Thaller, Anian, Schmauder, Lukas, Frieß, Wolfgang, Winter, Gerhard, Menzen, Tim, Hawe, Andrea, Richter, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678208/ https://www.ncbi.nlm.nih.gov/pubmed/36410586 http://dx.doi.org/10.1016/j.ejpb.2022.11.014 |
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